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Gilead Sciences - 27 Year Stock Price History | GILD

Historical daily share price chart and data for Gilead Sciences since 1992 adjusted for splits. The latest closing stock price for Gilead Sciences as of April 24, 2019 is 62.80.
  • The all-time high Gilead Sciences stock price is 111.59, which is 77.7% above the current share price.
  • The Gilead Sciences 52-week high stock price is 78.34, which is 24.7% above the current share price.
  • The Gilead Sciences 52-week low stock price is 60.54, which is 3.6% below the current share price.
  • The average Gilead Sciences stock price for the last 52 weeks is 69.34.
Gilead Sciences Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2019 66.2036 63.4400 70.0500 61.8700 62.8000 0.40%
2018 72.4550 71.8230 86.0713 60.5400 62.5500 -9.92%
2017 69.0094 69.8347 81.7515 60.8436 69.4386 2.97%
2016 77.6107 90.2269 94.6147 67.1529 67.4334 -27.61%
2015 97.2518 86.3445 111.5870 86.3445 93.1544 8.63%
2014 81.4943 68.4224 103.9118 59.5705 85.7531 25.51%
2013 51.0011 34.1430 68.4133 34.0929 68.3223 104.49%
2012 25.7100 19.0411 34.7252 19.0411 33.4106 79.45%
2011 18.1622 16.6393 19.6552 16.0753 18.6181 12.94%
2010 17.8632 19.6961 22.4936 14.4787 16.4847 -16.25%
2009 20.9767 23.7354 24.0174 18.8500 19.6825 -15.39%
2008 22.3728 20.6241 25.9734 17.0442 23.2623 11.15%
2007 18.0039 14.3627 21.7158 14.2672 20.9288 41.72%
2006 14.0807 12.4408 15.8638 12.2248 14.7675 23.51%
2005 9.6150 7.8989 12.6524 7.0597 11.9564 50.24%
2004 7.3176 6.5980 8.8792 5.8861 7.9580 20.08%
2003 5.8553 3.9677 7.9592 3.6731 6.6275 71.41%
2002 3.8727 3.4929 4.5158 3.0192 3.8664 3.47%
2001 2.8512 2.1075 4.1058 1.5369 3.7368 58.47%
2000 2.1420 1.6009 3.3035 1.2350 2.3580 53.23%
1999 1.5176 1.1301 2.6263 1.0164 1.5389 31.83%
1998 0.9068 1.0840 1.2296 0.5188 1.1673 7.35%
1997 0.8913 0.6965 1.3115 0.6149 1.0874 53.00%
1996 0.8062 0.9274 1.1585 0.4904 0.7107 -21.88%
1995 0.5241 0.2665 0.9169 0.2665 0.9098 236.84%
1994 0.2860 0.3412 0.3980 0.1990 0.2701 -20.84%
1993 0.4206 0.5188 0.5439 0.3056 0.3412 -37.66%
Sector Industry Market Cap Revenue
Medical Medical - Biomedical and Genetics $80.369B $22.127B
Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. The Company strive to transform and simplify care for people with life-threatening illnesses around the world. Gilead's portfolio of products and pipeline of investigational drugs includes treatments for HIV/AIDS, liver diseases, cancer, inflammatory and respiratory diseases, and cardiovascular conditions. Their portfolio of marketed products includes a number of category firsts, including complete treatment regimens for HIV infection available in a once-daily single pill and the first oral antiretroviral pill available to reduce the risk of acquiring HIV infection in certain high-risk adults.
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Galapagos (GLPG) Belgium $5.892B 0.00
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Alkermes (ALKS) Ireland $5.370B 0.00
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Ascendis Pharma (ASND) Denmark $4.724B 0.00
Horizon Pharma Public (HZNP) Ireland $4.659B 13.80
Spark Therapeutics (ONCE) United States $4.199B 0.00
ARGENX SE-ADR (ARGX) Netherlands $3.893B 0.00
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Intercept Pharmaceuticals (ICPT) United States $2.688B 0.00
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Mirati Therapeutics (MRTX) United States $2.270B 0.00
Arena Pharmaceuticals (ARNA) United States $2.256B 0.00
Acceleron Pharma (XLRN) United States $2.189B 0.00
Medicines (MDCO) United States $2.169B 0.00
UniQure (QURE) Netherlands $2.072B 0.00
CRISPR Therapeutics AG (CRSP) Switzerland $2.022B 0.00
Nabriva Therapeutics AG (NBRV) Ireland $1.993B 0.00
MyoKardia (MYOK) United States $1.978B 0.00
AnaptysBio (ANAB) United States $1.966B 0.00
REGENXBIO (RGNX) United States $1.926B 20.00
NeoGenomics (NEO) United States $1.923B 155.15
Zai Lab Unsponsored ADR (ZLAB) China $1.758B 0.00
Audentes Therapeutics (BOLD) United States $1.749B 0.00
Allakos (ALLK) United States $1.690B 0.00
Atara Biotherapeutics (ATRA) United States $1.546B 0.00
Orchard Therapeutics Sponsored ADR (ORTX) United Kingdom $1.534B 0.00
Alector (ALEC) United States $1.461B 0.00
Momenta Pharmaceuticals (MNTA) United States $1.448B 0.00
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Editas Medicine (EDIT) United States $1.347B 0.00
InflaRx (IFRX) Germany $1.340B 0.00
Puma Biotechnology (PBYI) United States $1.337B 0.00
Myovant Sciences (MYOV) United Kingdom $1.319B 0.00
Aimmune Therapeutics (AIMT) United States $1.309B 0.00
Rubius Therapeutics (RUBY) United States $1.267B 0.00
Sangamo Therapeutics (SGMO) United States $1.227B 0.00
Apellis Pharmaceuticals (APLS) United States $1.221B 0.00
Epizyme (EPZM) United States $1.153B 0.00
Gossamer Bio (GOSS) United States $1.127B 0.00
Clovis Oncology (CLVS) United States $1.104B 0.00
Fate Therapeutics (FATE) United States $1.102B 0.00
Codexis (CDXS) United States $1.100B 0.00
NGM BIOPHARMACT (NGM) United States $1.054B 0.00
Autolus Therapeutics Sponsored ADR (AUTL) United Kingdom $1.043B 0.00
Eidos Therapeutics (EIDX) United States $1.025B 0.00
Coherus BioSciences (CHRS) United States $0.983B 0.00
Inotek Pharmaceuticals (RCKT) United States $0.971B 0.00
Deciphera Pharmaceuticals (DCPH) United States $0.968B 0.00
Genfit SA (GNFT) France $0.964B 0.00
Dicerna Pharmaceuticals (DRNA) United States $0.955B 0.00
Alder BioPharmaceuticals (ALDR) United States $0.942B 0.00
RA PHARMCTL INC (RARX) United States $0.926B 0.00
WAVE Life Sciences (WVE) Singapore $0.921B 0.00
Twist Bioscience (TWST) United States $0.921B 0.00
Vanda Pharmaceuticals (VNDA) United States $0.911B 36.83
Rhythm Pharmaceuticals (RYTM) United States $0.893B 0.00
Kiniksa Pharmaceuticals (KNSA) Bermuda $0.873B 0.00
Cellectis (CLLS) France $0.857B 0.00
ANI Pharmaceuticals (ANIP) United States $0.825B 15.11
Y-mAbs Therapeutics (YMAB) United States $0.825B 0.00
Retrophin (RTRX) United States $0.817B 0.00
Vericel (VCEL) United States $0.780B 0.00
Intellia Therapeutics (NTLA) United States $0.771B 0.00
Athenex (ATNX) United States $0.760B 0.00
Cara Therapeutics (CARA) United States $0.748B 0.00
Arvinas (ARVN) United States $0.732B 0.00
G1 THERAPEUTICS (GTHX) United States $0.725B 0.00
Nightstar Therapeutics Sponsored ADR (NITE) United Kingdom $0.718B 0.00
Intra-Cellular Therapies (ITCI) United States $0.713B 0.00
Principia Biopharma (PRNB) United States $0.698B 0.00
ZIOPHARM Oncology Inc (ZIOP) United States $0.675B 0.00
Precision BioSciences (DTIL) United States $0.666B 0.00
Viking Therapeutics (VKTX) United States $0.628B 0.00
ObsEva SA (OBSV) Switzerland $0.625B 0.00
Lexicon Pharmaceuticals (LXRX) United States $0.621B 0.00
Stemline Therapeutics (STML) United States $0.610B 0.00
MeiraGTx Holdings (MGTX) United States $0.600B 0.00
Revance Therapeutics (RVNC) United States $0.598B 0.00
Kura Oncology (KURA) United States $0.594B 0.00
Heska (HSKA) United States $0.589B 52.85
Zealand Pharma (ZEAL) Denmark $0.578B 6.43
Synthorx (THOR) United States $0.575B 0.00
DBV Technologies (DBVT) France $0.541B 0.00
Acorda Therapeutics (ACOR) United States $0.540B 6.99
Zymeworks (ZYME) Canada $0.538B 0.00
Axsome Therapeutics (AXSM) United States $0.530B 0.00
UROGEN PHARMA (URGN) United States $0.519B 0.00
Magenta Therapeutics (MGTA) United States $0.519B 0.00
Mesoblast (MESO) Australia $0.519B 0.00
Cytokineticsorporated (CYTK) United States $0.496B 0.00
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Krystal Biotech (KRYS) United States $0.487B 0.00
AVROBIO (AVRO) United States $0.482B 0.00
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Replimune (REPL) United States $0.462B 0.00
Scholar Rock Holding (SRRK) United States $0.461B 0.00
Adaptimmune Therapeutics (ADAP) United Kingdom $0.461B 0.00
Sorrento Therapeutics (SRNE) United States $0.457B 0.00
ProQR Therapeutics (PRQR) Netherlands $0.454B 0.00
MediciNova (MNOV) United States $0.453B 0.00
CytomX Therapeutics (CTMX) United States $0.452B 0.00
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Senesco Technologies (ELOX) United States $0.448B 0.00
PDL BioPharma (PDLI) United States $0.446B 9.94
Prothena (PRTA) Ireland $0.446B 0.00
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KALEIDO BIOSCI (KLDO) $0.443B 0.00
CYCLERION THERA (CYCN) United States $0.424B 0.00
Dynavax Technologies (DVAX) United States $0.424B 0.00
Adverum Biotechnologies (ADVM) United States $0.418B 0.00
NuCana Sponsored ADR (NCNA) United Kingdom $0.417B 0.00
AMAG Pharmaceuticals (AMAG) United States $0.409B 0.00
Abeona Therapeutics (ABEO) United States $0.396B 0.00
Albireo Pharma (ALBO) United States $0.384B 0.00
Gritstone Oncology (GRTS) United States $0.378B 0.00
Kezar Life Sciences (KZR) United States $0.378B 0.00
Inovio Pharmaceuticals (INO) United States $0.377B 0.00
STEALTH BIOTHER (MITO) United States $0.373B 0.00
Sinovac Biotech (SVA) China $0.371B 0.00
Merus (MRUS) Netherlands $0.362B 0.00
Geron (GERN) United States $0.358B 0.00
Agenus (AGEN) United States $0.349B 0.00
BioDelivery Sciences (BDSI) United States $0.347B 0.00
Kindred Biosciences (KIN) United States $0.344B 0.00
UNITY Biotechnology (UBX) $0.342B 0.00
XBiotech (XBIT) United States $0.339B 0.00
Solid Biosciences (SLDB) United States $0.328B 0.00
AC Immune SA (ACIU) Switzerland $0.327B 0.00
BeyondSpring (BYSI) United States $0.326B 0.00
Constellation Pharmaceuticals (CNST) United States $0.321B 0.00
Cellular Biomedicine (CBMG) United States $0.321B 0.00
Biofrontera AG Sponsored ADR (BFRA) Germany $0.315B 0.00
PHASEBIO PHARMA (PHAS) United States $0.313B 0.00
MannKind (MNKD) United States $0.300B 0.00
Seres Therapeutics (MCRB) United States $0.287B 0.00
Aduro Biotech (ADRO) United States $0.282B 0.00
Kadmon Holdings (KDMN) United States $0.280B 0.00
LogicBio Therapeutics (LOGC) United States $0.273B 0.00
Evelo Biosciences (EVLO) United States $0.271B 0.00
Kodiak Sciences (KOD) United States $0.266B 0.00
Urovant Sciences (UROV) United States $0.261B 0.00
Enochian BioSciences (ENOB) United States $0.260B 0.00
Avid Bioservices (CDMO) United States $0.259B 0.00
Kala Pharmaceuticals (KALA) United States $0.256B 0.00
Cerecor (CERC) United States $0.248B 0.00
ResTORbio (TORC) United States $0.248B 0.00
Kamada (KMDA) Israel $0.246B 11.13
Strongbridge Biopharma (SBBP) United States $0.244B 0.00
Athersys (ATHX) United States $0.244B 0.00
Novavax (NVAX) United States $0.242B 0.00
Arsanis (XFOR) United States $0.237B 0.00
Xenon Pharmaceuticals (XENE) Canada $0.234B 0.00
ChromaDex (CDXC) United States $0.233B 0.00
Palatin Technologies (PTN) United States $0.231B 114.00
Sutro Biopharma (STRO) United States $0.231B 0.00
Protagonist Therapeutics (PTGX) United States $0.230B 0.00
Syros Pharmaceuticals (SYRS) United States $0.224B 0.00
ADMA Biologics Inc (ADMA) United States $0.219B 0.00
OSMOTICA PHARM (OSMT) United States $0.219B 0.00
Cel-Sci (CVM) United States $0.218B 0.00
Celcuity (CELC) United States $0.217B 0.00
Gamida Cell (GMDA) Israel $0.215B 0.00
Aeglea BioTherapeutics (AGLE) United States $0.214B 0.00
Spero Therapeutics (SPRO) United States $0.214B 0.00
Eiger BioPharmaceuticals (EIGR) United States $0.213B 0.00
OvaScience (MLND) United States $0.213B 0.00
Mersana Therapeutics (MRSN) United States $0.212B 0.00
Axovant Sciences (AXGT) United Kingdom $0.210B 0.00
Intec Pharma (NTEC) Israel $0.205B 0.00
Celyad SA (CYAD) Belgium $0.202B 0.00
CorMedix Inc (CRMD) United States $0.202B 0.00
TOCAGEN INC (TOCA) United States $0.200B 0.00
VBI Vaccines (VBIV) United States $0.195B 0.00
Synlogic (SYBX) United States $0.194B 0.00
BioTime (BTX) United States $0.188B 0.00
Paratek Pharmaceuticals (PRTK) United States $0.185B 0.00
Pfenex (PFNX) United States $0.183B 0.00
Compugen (CGEN) Israel $0.180B 0.00
Cue Biopharma (CUE) United States $0.175B 0.00
Syndax Pharmaceuticals (SNDX) United States $0.174B 0.00
Enzo Biochem (ENZ) United States $0.173B 0.00
Mustang Bio (MBIO) United States $0.171B 0.00
Menlo Therapeutics (MNLO) United States $0.169B 0.00
Arbutus Biopharma (ABUS) Canada $0.168B 0.00
Verastem (VSTM) United States $0.168B 0.00
EYEPOINT PHARMACEUTICALS, INC (EYPT) United States $0.162B 0.00
BioXcel Therapeutics (BTAI) United States $0.157B 0.00
AVEO Pharmaceuticals (AVEO) United States $0.148B 0.00
Chiasma (CHMA) United States $0.146B 0.00
Pieris Pharmaceuticals (PIRS) United States $0.145B 0.00
ASLAN Pharmaceuticals (ASLN) Singapore $0.144B 0.00
Anavex Life Sciences (AVXL) United States $0.139B 0.00
Erytech Pharma SA Sponsored ADR (ERYP) France $0.138B 0.00
Allena Pharmaceuticals (ALNA) United States $0.136B 0.00
Trevena (TRVN) United States $0.135B 0.00
Eton Pharmaceuticals (ETON) United States $0.135B 0.00
Checkpoint Therapeutics (CKPT) United States $0.134B 0.00
VolitionRX (VNRX) Singapore $0.131B 0.00
Nymox Pharmaceutical (NYMX) Canada $0.131B 0.00
Liquidia Technologies (LQDA) United States $0.128B 0.00
Aptinyx (APTX) United States $0.128B 0.00
Corvus Pharmaceuticals (CRVS) United States $0.127B 0.00
Provention Bio (PRVB) United States $0.125B 0.00
Organovo Holdings (ONVO) United States $0.121B 0.00
Brainstorm Cell Therapeutics (BCLI) United States $0.112B 0.00
Neothetics (EVFM) United States $0.111B 0.00
Unum Therapeutics (UMRX) United States $0.109B 0.00
XOMA (XOMA) United States $0.108B 0.00
Spring Bank Pharmaceuticals (SBPH) United States $0.105B 0.00
INMUNE BIO INC (INMB) United States $0.104B 0.00
Catalyst Biosciences (CBIO) United States $0.103B 0.00
Selecta Biosciences (SELB) United States $0.101B 0.00
Fortress Biotech (FBIO) United States $0.100B 0.00
Cohbar (CWBR) United States $0.097B 0.00
Dyadic (DYAI) United States $0.094B 0.00
Equillium (EQ) United States $0.094B 0.00
Catabasis Pharmaceuticals (CATB) United States $0.094B 0.00
Signal Genetics (MGEN) United States $0.090B 0.00
NantKwest (NK) United States $0.089B 0.00
Sunesis Pharmaceuticals (SNSS) United States $0.088B 0.00
Applied Genetic Technologies (AGTC) United States $0.087B 0.00
Verona Pharma American Depositary Share (VRNA) United Kingdom $0.084B 0.00
ANIXA BIOSCIENCES INC (ANIX) United States $0.084B 0.00
SESEN BIO, INC (SESN) United States $0.083B 0.00
Aridis Pharmaceuticals (ARDS) United States $0.082B 0.00
Merrimack Pharmaceuticals (MACK) United States $0.081B 0.00
Cocrystal Pharma (COCP) United States $0.081B 85.00
Alcobra (ARCT) United States $0.078B 0.00
ARAVIVE, INC (ARAV) United States $0.077B 0.00
Tiziana Life Sciences Sponsored ADR (TLSA) United Kingdom $0.077B 0.00
Aptose Biosciences (APTO) Canada $0.077B 0.00
OVID THERAPEUTC (OVID) United States $0.076B 0.00
Eyenovia (EYEN) United States $0.075B 0.00
Orgenesis (ORGS) United States $0.072B 0.00
Vaccinex (VCNX) United States $0.072B 0.00
Idera Pharmaceuticals (IDRA) United States $0.071B 0.00
Zosano Pharma (ZSAN) United States $0.067B 0.00
AEterna Zentaris (AEZS) United States $0.066B 16.08
Apricus Biosciences (SEEL) United States $0.065B 0.00
Cidara Therapeutics (CDTX) United States $0.064B 0.00
Alimera Sciences (ALIM) United States $0.064B 0.00
Pluristem Therapeutics (PSTI) Israel $0.063B 0.00
Protalix BioTherapeutics (PLX) Israel $0.063B 0.00
NewLink Genetics (NLNK) United States $0.062B 0.00
VTv Therapeutics (VTVT) United States $0.062B 0.00
Curis (CRIS) United States $0.061B 0.00
Sienna Biopharmaceuticals (SNNA) United States $0.061B 0.00
Proteostasis Therapeutics (PTI) United States $0.061B 0.00
Ophthotech (ISEE) United States $0.060B 0.00
Akari Therapeutics (AKTX) United Kingdom $0.059B 0.00
Evogene (EVGN) Israel $0.057B 0.00
ScPharmaceuticals (SCPH) United States $0.057B 0.00
Moleculin Biotech (MBRX) United States $0.055B 0.00
Prima BioMed (IMMP) Australia $0.054B 0.00
AquaBounty Technologies (AQB) United States $0.051B 0.00
INNOVATE BIOPHARMACEUTICALS, INC (INNT) United States $0.050B 0.00
HOTH THERAPEUTC (HOTH) United States $0.050B 0.00
Celldex Therapeutics (CLDX) United States $0.049B 0.00
Entera Bio (ENTX) Israel $0.049B 0.00
AZURRX BIOPHARM (AZRX) United States $0.048B 0.00
Vascular Biogenics (VBLT) Israel $0.047B 0.00
BiondVax Pharmaceuticals (BVXV) Israel $0.047B 0.00
Clearside Biomedical (CLSD) United States $0.047B 0.00
Celsion (CLSN) United States $0.047B 0.00
VistaGen Therapeutics (VTGN) United States $0.046B 0.00
Bellerophon Therapeutics (BLPH) United States $0.045B 0.00
Bionano Genomics (BNGO) United States $0.044B 0.00
ANCHIANO THERAP (ANCN) Israel $0.043B 0.00
Aerpio Pharmaceuticals (ARPO) United States $0.043B 0.00
DiaMedica Therapeutics (DMAC) United States $0.040B 0.00
VIVUS (VVUS) United States $0.038B 0.00
OncoSec Medical (ONCS) United States $0.038B 0.00
Leap Therapeutics (LPTX) United States $0.037B 0.00
OncoMed Pharmaceuticals (OMED) United States $0.034B 0.00
Aptevo Therapeutics (APVO) United States $0.034B 0.00
Oncolytics Biotech (ONCY) Canada $0.033B 0.00
Motif Bio Plc (MTFB) United States $0.032B 0.00
Caladrius Biosciences (CLBS) United States $0.030B 0.00
Sophiris Bio (SPHS) United States $0.029B 0.00
GTx (GTXI) United States $0.028B 0.00
GENPREX INC (GNPX) United States $0.028B 0.00
Adial Pharmaceuticals (ADIL) United States $0.026B 0.00
Novelion Therapeutics (NVLN) Canada $0.026B 0.00
Aileron Therapeutics (ALRN) United States $0.026B 0.00
Vical (VICL) United States $0.025B 0.00
Rexahn Pharmaceuticals (RNN) United States $0.025B 0.00
Aytu Bioscience (AYTU) United States $0.024B 0.00
Titan Pharmaceuticals (TTNP) United States $0.024B 0.00
Oragenics (OGEN) United States $0.023B 0.00
Fibrocell Science Inc (FCSC) United States $0.022B 0.00
Galena Biopharma (SLS) United States $0.021B 0.00
ATyr Pharma (LIFE) United States $0.021B 0.00
TRACON Pharmaceuticals (TCON) United States $0.020B 0.00
IMMURON LTD (IMRN) Australia $0.020B 0.00
Advaxis (ADXS) United States $0.019B 0.00
Benitec Biopharma (BNTC) Australia $0.019B 0.00
TrovaGene (TROV) United States $0.019B 0.00
CytRx (CYTR) United States $0.019B 0.00
Gemphire Therapeutics (GEMP) United States $0.019B 0.00
Vital Therapies (IMUX) United States $0.018B 0.00
Oncobiologics (OTLK) United States $0.018B 0.00
Cleveland BioLabs (CBLI) United States $0.018B 0.00
Histogenics (HSGX) United States $0.018B 0.00
Novogen (KZIA) Australia $0.017B 0.00
BioPharmX (BPMX) United States $0.017B 0.00
Prana Biotechnology (ATHE) Australia $0.016B 0.00
IBio (IBIO) United States $0.016B 0.00
Alliqua BioMedical (ALQA) United States $0.014B 0.00
Genetic Technologies (GENE) Australia $0.013B 0.00
Cyclacel Pharmaceuticals (CYCC) United States $0.012B 0.00
Soligenix (SNGX) United States $0.012B 0.00
MYOS RENS Technology (MYOS) United States $0.012B 0.00
Therapix Biosciences (TRPX) Israel $0.012B 5.96
Dare Bioscience (DARE) United States $0.012B 0.00
Neuralstem (CUR) United States $0.011B 0.00
Flex Pharma (FLKS) United States $0.010B 0.00
AmpliPhi Biosciences (APHB) United States $0.010B 0.00
Tenax Therapeutics (TENX) United States $0.010B 0.00
RestorGenex (DFFN) United States $0.009B 0.00
Edge Therapeutics (PDSB) United States $0.009B 0.00
Hemispherx BioPharma (HEB) United States $0.009B 0.00
Synthetic Biologics (SYN) United States $0.009B 0.00
Pulmatrix (PULM) United States $0.009B 0.00
Proteon Therapeutics (PRTO) United States $0.008B 0.00
ARCA Biopharma (ABIO) United States $0.006B 0.00
Stellar Biotechnologies (SBOT) United States $0.006B 0.00
Cytori Therapeutics Inc (CYTX) United States $0.005B 0.00
Cellect Biotechnology (APOP) Israel $0.005B 0.00
ContraVir Pharmaceuticals Inc (CTRV) United States $0.004B 0.00