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DURECT - 25 Year Stock Price History | DRRX

Historical daily share price chart and data for DURECT since 2000 adjusted for splits and dividends. The latest closing stock price for DURECT as of March 20, 2025 is 0.80.
  • The all-time high DURECT stock closing price was 158.10 on November 06, 2000.
  • The DURECT 52-week high stock price is 1.88, which is 135% above the current share price.
  • The DURECT 52-week low stock price is 0.70, which is 12.5% below the current share price.
  • The average DURECT stock price for the last 52 weeks is 1.15.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
DURECT Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 0.8014 0.7908 0.8700 0.7474 0.8000 6.67%
2024 1.1587 0.5550 1.7800 0.5215 0.7500 27.12%
2023 3.8218 3.6000 8.7200 0.5020 0.5900 -82.95%
2022 5.6450 9.7500 9.7500 3.3900 3.4600 -64.91%
2021 16.0516 21.0000 28.7000 8.9560 9.8590 -52.37%
2020 20.0734 26.1500 28.5000 9.6780 20.7000 -45.53%
2019 11.8597 5.4020 38.0000 5.1200 38.0000 686.59%
2018 14.2259 9.2020 25.1000 4.8310 4.8310 -47.59%
2017 12.6894 13.4000 21.0000 7.7580 9.2180 -31.21%
2016 13.7067 20.4000 20.4000 10.1000 13.4000 -39.37%
2015 20.0206 8.3000 32.3000 8.3000 22.1000 180.03%
2014 14.1437 17.3000 22.2000 6.9570 7.8920 -54.38%
2013 12.3986 9.6000 17.5000 7.7080 17.3000 88.04%
2012 9.5235 12.0000 16.6000 6.9410 9.2000 -22.03%
2011 24.2069 35.9000 37.3000 11.5000 11.8000 -65.80%
2010 25.9768 25.6000 36.1500 19.5000 34.5000 39.68%
2009 24.4722 33.0000 33.9000 14.4000 24.7000 -27.14%
2008 46.5304 62.1000 64.3000 28.7000 33.9000 -47.28%
2007 47.9036 43.9000 69.0000 36.8000 64.3000 44.82%
2006 44.8082 50.7000 63.6000 27.6000 44.4000 -12.43%
2005 46.1865 31.2000 71.8000 26.4000 50.7000 54.57%
2004 26.7017 26.4000 42.3000 12.6000 32.8000 31.20%
2003 24.3238 21.2000 40.0000 11.2000 25.0000 23.76%
2002 62.5330 110.5000 116.0000 19.7000 20.2000 -82.57%
2001 88.3911 111.3000 140.0000 40.0000 115.9000 -3.42%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.025B $0.009B
Durect Corp. is pioneering the treatment of chronic diseases and conditions by developing and commercializing pharmaceutical systems to deliver the right drug to the right place in the right amount at the right time. Its pharmaceutical systems combine engineering innovations and delivery technology from the medical device and drug delivery industries with its proprietary pharmaceutical and biotechnology drug formulations.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $83.625B 33.00
Zoetis (ZTS) United States $74.024B 27.92
Takeda Pharmaceutical (TAK) Japan $44.801B 9.92
Daiichi Sankyo, - (DSNKY) Japan $43.243B 26.35
Sandoz Group AG (SDZNY) Switzerland $20.284B 0.00
Merck (MKKGY) Germany $18.475B 16.55
Astellas Pharma (ALPMY) Japan $17.608B 12.47
United Therapeutics (UTHR) United States $15.992B 15.73
Summit Therapeutics (SMMT) United States $13.894B 0.00
Shionogi (SGIOY) Japan $12.709B 12.73
Neurocrine Biosciences (NBIX) United States $11.876B 36.20
Orion OYJ (ORINY) Finland $7.630B 21.45
Madrigal Pharmaceuticals (MDGL) United States $7.026B 0.00
Corcept Therapeutics (CORT) United States $6.476B 49.06
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.416B 0.00
Stevanato Group S.p.A (STVN) Italy $6.396B 41.41
Grifols, S.A (GRFS) Spain $5.109B 0.00
Ionis Pharmaceuticals (IONS) United States $5.069B 0.00
Ono Pharmaceutical (OPHLF) Japan $4.650B 9.52
Recursion Pharmaceuticals (RXRX) United States $3.517B 0.00
Crinetics Pharmaceuticals (CRNX) United States $3.211B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.572B 15.37
Catalyst Pharmaceuticals (CPRX) United States $2.535B 11.49
Hypermarcas (HYPMY) Brazil $2.065B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $2.065B 0.00
Soleno Therapeutics (SLNO) United States $1.941B 0.00
BioCryst Pharmaceuticals (BCRX) United States $1.717B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $1.620B 0.00
Evotec AG (EVO) Germany $1.581B 0.00
Dyne Therapeutics (DYN) United States $1.383B 0.00
Guardian Pharmacy Services (GRDN) United States $1.264B 0.00
Ardelyx (ARDX) United States $1.223B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.153B 0.00
Indivior (INDV) United States $1.138B 4.94
Ocular Therapeutix (OCUL) United States $1.058B 0.00
Xencor (XNCR) United States $1.054B 0.00
ARS Pharmaceuticals (SPRY) United States $1.053B 0.00
Enliven Therapeutics (ELVN) United States $1.043B 0.00
Harrow (HROW) United States $0.982B 0.00
Collegium Pharmaceutical (COLL) United States $0.941B 5.14
Bioventus (BVS) United States $0.814B 25.72
Avadel Pharmaceuticals (AVDL) Ireland $0.795B 0.00
Cronos Group (CRON) Canada $0.734B 0.00
Relay Therapeutics (RLAY) United States $0.649B 0.00
USANA Health Sciences (USNA) United States $0.623B 11.55
Verve Therapeutics (VERV) United States $0.595B 0.00
Xeris Biopharma Holdings (XERS) United States $0.561B 0.00
Elite Pharmaceuticals (ELTP) United States $0.526B 0.00
OmniAb (OABI) United States $0.514B 0.00
KalVista Pharmaceuticals (KALV) United States $0.511B 0.00
Savara (SVRA) United States $0.455B 0.00
CytoDyn (CYDY) United States $0.440B 0.00
ProKidney (PROK) United States $0.437B 0.00
Theravance Biopharma (TBPH) Cayman Islands $0.436B 0.00
Altimmune (ALT) United States $0.435B 0.00
Siga Technologies (SIGA) United States $0.406B 4.74
Organogenesis (ORGO) United States $0.400B 0.00
Zevra Therapeutics (ZVRA) United States $0.398B 0.00
Aldeyra Therapeutics (ALDX) United States $0.387B 0.00
Akebia Therapeutics (AKBA) United States $0.386B 0.00
Oruka Therapeutics (ORKA) United States $0.380B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.377B 152.79
Esperion Therapeutics (ESPR) United States $0.359B 0.00
Tourmaline Bio (TRML) United States $0.314B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.288B 0.00
Aquestive Therapeutics (AQST) United States $0.270B 0.00
Heron Therapeutics (HRTX) United States $0.269B 0.00
Nature's Sunshine Products (NATR) United States $0.255B 15.19
Avita Medical (RCEL) United States $0.247B 0.00
Innate Pharma SA (IPHYF) France $0.243B 0.00
Korro Bio (KRRO) United States $0.239B 0.00
Profound Medical (PROF) Canada $0.224B 0.00
4D Molecular Therapeutics (FDMT) United States $0.209B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.206B 0.00
Lyell Immunopharma (LYEL) United States $0.194B 0.00
MediWound (MDWD) Israel $0.194B 0.00
Larimar Therapeutics (LRMR) United States $0.193B 0.00
Nanobiotix S.A (NBTX) France $0.182B 0.00
Enanta Pharmaceuticals (ENTA) United States $0.178B 0.00
Inhibikase Therapeutics (IKT) United States $0.172B 0.00
Acrivon Therapeutics (ACRV) United States $0.168B 0.00
Nektar Therapeutics (NKTR) United States $0.156B 0.00
Aclaris Therapeutics (ACRS) United States $0.148B 0.00
Silence Therapeutics (SLN) United Kingdom $0.146B 0.00
Inotiv (NOTV) United States $0.137B 0.00
Champions Oncology (CSBR) United States $0.129B 0.00
Telomir Pharmaceuticals (TELO) United States $0.126B 0.00
Lexeo Therapeutics (LXEO) United States $0.123B 0.00
Cassava Sciences (SAVA) United States $0.120B 0.00
Procaps Group, S.A (PROCF) Luxembourg $0.120B 0.00
ElectroCore (ECOR) United States $0.115B 0.00
VAXART, INC (VXRT) United States $0.115B 0.00
Journey Medical (DERM) United States $0.112B 0.00
Achieve Life Sciences (ACHV) Canada $0.108B 0.00
Cardiol Therapeutics (CRDL) Canada $0.097B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.092B 0.00
Galectin Therapeutics (GALT) United States $0.092B 0.00
Arch Biopartners (ACHFF) Canada $0.087B 0.00
Metagenomi (MGX) United States $0.087B 0.00
Regulus Therapeutics (RGLS) United States $0.085B 0.00
Nutriband (NTRB) United States $0.084B 0.00
Avalo Therapeutics (AVTX) United States $0.084B 0.00
ESSA Pharma (EPIX) Canada $0.076B 0.00
Assertio Holdings (ASRT) United States $0.076B 19.92
Karyopharm Therapeutics (KPTI) United States $0.075B 0.00
PMV Pharmaceuticals (PMVP) United States $0.074B 0.00
Protara Therapeutics (TARA) United States $0.074B 0.00
Pyxis Oncology (PYXS) United States $0.073B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.071B 0.00
Fractyl Health (GUTS) United States $0.068B 0.00
Vivani Medical (VANI) United States $0.068B 0.00
Mural Oncology (MURA) Ireland $0.066B 0.00
Context Therapeutics (CNTX) United States $0.062B 0.00
Century Therapeutics (IPSC) United States $0.061B 0.00
AleAnna (ANNA) United States $0.060B 0.00
Unicycive Therapeutics (UNCY) United States $0.059B 0.00
FibroGen (FGEN) United States $0.058B 0.00
OptiNose (OPTN) United States $0.057B 0.00
Gain Therapeutics (GANX) United States $0.055B 0.00
AlloVir (ALVR) United States $0.051B 0.00
Iterum Therapeutics (ITRM) Ireland $0.050B 0.00
Rafael Holdings (RFL) United States $0.049B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.049B 0.00
Dominari Holdings (DOMH) United States $0.048B 0.00
Prelude Therapeutics (PRLD) United States $0.046B 0.00
VYNE Therapeutics (VYNE) United States $0.041B 0.00
NRx Pharmaceuticals (NRXP) United States $0.040B 0.00
SCYNEXIS (SCYX) United States $0.039B 0.00
Tempest Therapeutics (TPST) United States $0.038B 0.00
CASI Pharmaceuticals (CASI) China $0.037B 0.00
Surrozen (SRZN) United States $0.037B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.031B 0.00
PolyPid (PYPD) Israel $0.031B 0.00
Incannex Healthcare (IXHL) Australia $0.027B 0.00
BioVie (BIVI) United States $0.027B 0.00
Jupiter Neurosciences (JUNS) United States $0.026B 0.00
Natural Alternatives (NAII) United States $0.025B 0.00
Scienture Holdings (SCNX) United States $0.023B 0.00
Enlivex Therapeutics (ENLV) Israel $0.021B 0.00
Mannatech (MTEX) United States $0.021B 0.00
Vivos Therapeutics (VVOS) United States $0.020B 0.00
Carisma Therapeutics (CARM) United States $0.018B 0.00
GlycoMimetics (GLYC) United States $0.018B 0.00
MEI Pharma (MEIP) United States $0.018B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.017B 0.00
Lipocine (LPCN) United States $0.017B 0.00
Tonix Pharmaceuticals Holding (TNXP) United States $0.016B 0.00
Citius Pharmaceuticals (CTXR) United States $0.015B 0.00
Traws Pharma (TRAW) United States $0.015B 0.00
Biomerica (BMRA) United States $0.014B 0.00
Lyra Therapeutics (LYRA) United States $0.014B 0.00
Cosmos Health (COSM) United States $0.013B 0.00
ProPhase Labs (PRPH) United States $0.013B 0.00
Minerva Neurosciences (NERV) United States $0.013B 0.00
BioLineRx (BLRX) Israel $0.012B 0.00
Nuvilex (PMCB) United States $0.012B 0.00
TherapeuticsMD (TXMD) United States $0.012B 0.00
Mangoceuticals (MGRX) United States $0.011B 0.00
Indaptus Therapeutics (INDP) United States $0.011B 0.00
Phio Pharmaceuticals (PHIO) United States $0.011B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.010B 0.00
Klotho Neurosciences (KLTO) United States $0.010B 0.00
Addex Therapeutics (ADXN) Switzerland $0.010B 0.00
Talphera (TLPH) United States $0.009B 0.00
Jaguar Animal Health (JAGX) United States $0.009B 0.00
Ainos (AIMD) United States $0.009B 0.00
Relmada Therapeutics (RLMD) United States $0.009B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.008B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.007B 0.00
Plus Therapeutics (PSTV) United States $0.007B 0.00
Redhill Biopharma (RDHL) Israel $0.006B 0.00
Xenetic Biosciences (XBIO) United States $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.005B 0.00
Clearmind Medicine (CMND) Canada $0.005B 0.00
CERo Therapeutics Holdings (CERO) United States $0.005B 0.00
TransCode Therapeutics (RNAZ) United States $0.005B 0.00
Conduit Pharmaceuticals (CDT) United States $0.004B 0.00
SciSparc (SPRC) Israel $0.004B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.004B 0.00
InMed Pharmaceuticals (INM) Canada $0.004B 0.00
China SXT Pharmaceuticals (SXTC) China $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.003B 0.00
Avenue Therapeutics (ATXI) United States $0.003B 0.07
Alaunos Therapeutics (TCRT) United States $0.003B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.002B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.002B 0.00
SHINECO (SISI) China $0.002B 0.00
Heatwurx (PCSA) United States $0.002B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.002B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.002B 0.00
Petros Pharmaceuticals (PTPI) United States $0.001B 0.00
Aditxt (ADTX) United States $0.001B 0.00
TNF Pharmaceuticals (TNFA) United States $0.001B 0.00
PainReform (PRFX) Israel $0.000B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
4D Pharma (LBPS) United Kingdom $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00