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Lyra Therapeutics - 5 Year Stock Price History | LYRA

Historical daily share price chart and data for Lyra Therapeutics since 2020 adjusted for splits and dividends. The latest closing stock price for Lyra Therapeutics as of July 28, 2025 is 7.80.
  • The all-time high Lyra Therapeutics stock closing price was 928.00 on May 01, 2020.
  • The Lyra Therapeutics 52-week high stock price is 37.50, which is 380.8% above the current share price.
  • The Lyra Therapeutics 52-week low stock price is 3.81, which is 51.2% below the current share price.
  • The average Lyra Therapeutics stock price for the last 52 weeks is 10.38.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Lyra Therapeutics Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 8.7867 10.8000 27.5800 4.2500 7.8000 -24.27%
2024 99.2810 260.0000 326.5000 8.4000 10.3000 -96.07%
2023 155.8436 154.5000 262.0000 97.5000 262.0000 66.88%
2022 246.5966 234.0000 375.5000 122.0000 157.0000 -27.98%
2021 442.7528 562.0000 780.5000 211.0000 218.0000 -61.75%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.010B $0.002B
Lyra Therapeutics Inc. is a clinical-stage therapeutics company. It is focused on the development and commercialization of novel integrated drug and delivery solutions for patients with ear, nose and throat diseases. The company's proprietary technology platform, XTreo(TM), is designed to precisely and consistently deliver medicines directly to the affected tissue. Its initial product candidates consist LYR-210 and LYR-220 which are in clinical stage. Lyra Therapeutics Inc. is based in Watertown, Mass.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $81.683B 31.42
Zoetis (ZTS) United States $67.115B 25.04
Daiichi Sankyo, - (DSNKY) Japan $46.355B 23.76
Takeda Pharmaceutical (TAK) Japan $45.533B 9.06
BeOne Medicines - (ONC) Cayman Islands $32.278B 0.00
Sandoz Group AG (SDZNY) Switzerland $26.052B 0.00
Summit Therapeutics (SMMT) United States $20.386B 0.00
Merck (MKKGY) Germany $16.931B 12.40
Shionogi (SGIOY) Japan $15.006B 15.03
United Therapeutics (UTHR) United States $13.448B 11.90
Neurocrine Biosciences (NBIX) United States $13.233B 45.33
Orion OYJ (ORINY) Finland $11.504B 27.72
IPSEN (IPSEY) France $10.846B 0.00
Stevanato Group S.p.A (STVN) Italy $7.865B 48.09
Corcept Therapeutics (CORT) United States $7.333B 59.61
Grifols, S.A (GRFS) Spain $6.937B 0.00
Ionis Pharmaceuticals (IONS) United States $6.553B 0.00
Madrigal Pharmaceuticals (MDGL) United States $6.531B 0.00
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.204B 0.00
Ono Pharmaceutical (OPHLF) Japan $5.214B 15.86
Soleno Therapeutics (SLNO) United States $4.296B 0.00
Hypermarcas (HYPMY) Brazil $2.971B 19.54
Crinetics Pharmaceuticals (CRNX) United States $2.837B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $2.629B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.561B 13.85
Catalyst Pharmaceuticals (CPRX) United States $2.537B 8.89
Centessa Pharmaceuticals (CNTA) United Kingdom $2.031B 0.00
Ocular Therapeutix (OCUL) United States $1.924B 0.00
Endo (NDOI) United States $1.813B 0.00
ARS Pharmaceuticals (SPRY) United States $1.802B 0.00
BioCryst Pharmaceuticals (BCRX) United States $1.728B 0.00
Evotec AG (EVO) Germany $1.513B 0.00
Guardian Pharmacy Services (GRDN) United States $1.313B 0.00
Harrow (HROW) United States $1.279B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.201B 24.03
Dyne Therapeutics (DYN) United States $1.058B 0.00
Avadel Pharmaceuticals (AVDL) Ireland $1.048B 0.00
Ardelyx (ARDX) United States $1.024B 0.00
Enliven Therapeutics (ELVN) United States $1.014B 0.00
Collegium Pharmaceutical (COLL) United States $1.008B 5.43
Akebia Therapeutics (AKBA) United States $0.943B 0.00
ProKidney (PROK) United States $0.902B 0.00
Cronos Group (CRON) Canada $0.795B 0.00
Xeris Biopharma Holdings (XERS) United States $0.793B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.712B 0.00
KalVista Pharmaceuticals (KALV) United States $0.678B 0.00
Xencor (XNCR) United States $0.643B 0.00
Organogenesis (ORGO) United States $0.637B 0.00
Relay Therapeutics (RLAY) United States $0.634B 0.00
Zevra Therapeutics (ZVRA) United States $0.591B 0.00
Elite Pharmaceuticals (ELTP) United States $0.587B 0.00
USANA Health Sciences (USNA) United States $0.586B 11.77
Tourmaline Bio (TRML) United States $0.581B 0.00
Theravance Biopharma (TBPH) United States $0.553B 0.00
Bioventus (BVS) United States $0.536B 13.60
Oruka Therapeutics (ORKA) United States $0.525B 0.00
Siga Technologies (SIGA) United States $0.515B 10.76
Savara (SVRA) United States $0.460B 0.00
Aquestive Therapeutics (AQST) United States $0.397B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.357B 9.66
Tonix Pharmaceuticals Holding (TNXP) United States $0.348B 0.00
Altimmune (ALT) United States $0.327B 0.00
AleAnna (ANNA) United States $0.321B 0.00
Aldeyra Therapeutics (ALDX) United States $0.319B 0.00
Esperion Therapeutics (ESPR) United States $0.315B 0.00
Nanobiotix S.A (NBTX) France $0.313B 0.00
Nektar Therapeutics (NKTR) United States $0.293B 0.00
Heron Therapeutics (HRTX) United States $0.284B 0.00
Nature's Sunshine Products (NATR) United States $0.272B 24.97
OmniAb (OABI) United States $0.252B 0.00
Larimar Therapeutics (LRMR) United States $0.233B 0.00
MediWound (MDWD) Israel $0.215B 0.00
4D Molecular Therapeutics (FDMT) United States $0.215B 0.00
Liminatus Pharma (LIMN) United States $0.210B 0.00
Lyell Immunopharma (LYEL) United States $0.203B 0.00
Galectin Therapeutics (GALT) United States $0.194B 0.00
Aclaris Therapeutics (ACRS) United States $0.182B 0.00
China SXT Pharmaceuticals (SXTC) China $0.181B 0.00
Journey Medical (DERM) United States $0.179B 0.00
Profound Medical (PROF) Canada $0.171B 0.00
Avita Medical (RCEL) United States $0.153B 0.00
Korro Bio (KRRO) United States $0.147B 0.00
Lexeo Therapeutics (LXEO) United States $0.141B 0.00
Inhibikase Therapeutics (IKT) United States $0.132B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.129B 0.00
Protara Therapeutics (TARA) United States $0.129B 0.00
Cardiol Therapeutics (CRDL) Canada $0.126B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.117B 0.00
Cassava Sciences (SAVA) United States $0.115B 0.00
Innate Pharma SA (IPHYF) France $0.110B 0.00
Fractyl Health (GUTS) United States $0.096B 0.00
Vivani Medical (VANI) United States $0.095B 0.00
Metagenomi (MGX) United States $0.094B 0.00
Achieve Life Sciences (ACHV) Canada $0.093B 0.00
VAXART, INC (VXRT) United States $0.093B 0.00
Nutriband (NTRB) United States $0.090B 0.00
Champions Oncology (CSBR) United States $0.087B 19.69
ESSA Pharma (EPIX) Canada $0.083B 0.00
Arch Biopartners (ACHFF) Canada $0.080B 0.00
Surrozen (SRZN) United States $0.080B 0.00
PMV Pharmaceuticals (PMVP) United States $0.078B 0.00
Dominari Holdings (DOMH) United States $0.077B 0.00
Context Therapeutics (CNTX) United States $0.076B 0.00
Pyxis Oncology (PYXS) United States $0.076B 0.00
Wellgistics Health (WGRX) United States $0.075B 0.00
Inotiv (NOTV) United States $0.074B 0.00
Avalo Therapeutics (AVTX) United States $0.071B 0.00
Rafael Holdings (RFL) United States $0.071B 0.00
Assertio Holdings (ASRT) United States $0.069B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.063B 0.00
Telomir Pharmaceuticals (TELO) United States $0.063B 0.00
Unicycive Therapeutics (UNCY) United States $0.060B 0.00
Allergy Therapeutics (AGYTF) United Kingdom $0.059B 0.00
Century Therapeutics (IPSC) United States $0.055B 0.00
ElectroCore (ECOR) United States $0.054B 0.00
Jupiter Neurosciences (JUNS) United States $0.052B 0.00
BioNxt Solutions (BNXTF) Canada $0.052B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.052B 38.67
Klotho Neurosciences (KLTO) United States $0.052B 0.00
NRx Pharmaceuticals (NRXP) United States $0.051B 0.00
Gain Therapeutics (GANX) United States $0.049B 0.00
Prelude Therapeutics (PRLD) United States $0.048B 0.00
Acrivon Therapeutics (ACRV) United States $0.045B 0.00
Mural Oncology (MURA) Ireland $0.042B 0.00
Karyopharm Therapeutics (KPTI) United States $0.038B 0.00
PolyPid (PYPD) Israel $0.037B 0.00
Plus Therapeutics (PSTV) United States $0.035B 0.00
Incannex Healthcare (IXHL) Australia $0.035B 0.00
Iterum Therapeutics (ITRM) Ireland $0.031B 0.00
Enlivex Therapeutics (ENLV) Israel $0.030B 0.00
Tempest Therapeutics (TPST) United States $0.030B 0.00
FibroGen (FGEN) United States $0.029B 0.00
SCYNEXIS (SCYX) United States $0.029B 0.00
Vivos Therapeutics (VVOS) United States $0.028B 0.00
Scienture Holdings (SCNX) United States $0.026B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.024B 0.00
Natural Alternatives (NAII) United States $0.022B 0.00
VYNE Therapeutics (VYNE) United States $0.022B 0.00
Relmada Therapeutics (RLMD) United States $0.021B 0.00
Cosmos Health (COSM) United States $0.020B 0.00
CASI Pharmaceuticals (CASI) China $0.020B 0.00
ProPhase Labs (PRPH) United States $0.018B 0.00
Lipocine (LPCN) United States $0.018B 0.00
BioLineRx (BLRX) Israel $0.018B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.018B 0.00
DURECT (DRRX) United States $0.017B 0.00
Citius Pharmaceuticals (CTXR) United States $0.016B 0.00
Mannatech (MTEX) United States $0.016B 0.00
Carisma Therapeutics (CARM) United States $0.015B 0.00
Minerva Neurosciences (NERV) United States $0.015B 2.56
Ernexa Therapeutics (ERNA) United States $0.014B 0.00
TherapeuticsMD (TXMD) United States $0.014B 0.00
BioVie (BIVI) United States $0.013B 0.00
Phio Pharmaceuticals (PHIO) United States $0.012B 0.00
TransCode Therapeutics (RNAZ) United States $0.012B 0.00
Ainos (AIMD) United States $0.011B 0.00
Biomerica (BMRA) United States $0.010B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.009B 0.00
Addex Therapeutics (ADXN) Switzerland $0.009B 0.00
Traws Pharma (TRAW) United States $0.009B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.009B 0.00
Talphera (TLPH) United States $0.009B 0.00
Mangoceuticals (MGRX) United States $0.009B 0.00
Aptorum Group (APM) United Kingdom $0.009B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.007B 0.00
Nuvilex (PMCB) United States $0.007B 0.00
Indaptus Therapeutics (INDP) United States $0.006B 0.00
Xenetic Biosciences (XBIO) United States $0.006B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.005B 0.00
InMed Pharmaceuticals (INM) Canada $0.005B 0.00
Alaunos Therapeutics (TCRT) United States $0.005B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.005B 0.00
Qualigen Therapeutics (QLGN) United States $0.005B 0.00
Clearmind Medicine (CMND) Canada $0.004B 0.00
SciSparc (SPRC) Israel $0.004B 0.00
Redhill Biopharma (RDHL) Israel $0.004B 0.00
SHINECO (SISI) China $0.003B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
PainReform (PRFX) Israel $0.003B 0.00
CERo Therapeutics Holdings (CERO) United States $0.003B 0.00
Heatwurx (PCSA) United States $0.003B 0.00
Aditxt (ADTX) United States $0.003B 0.00
Jaguar Animal Health (JAGX) United States $0.002B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.002B 0.00
TNF Pharmaceuticals (TNFA) United States $0.002B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.002B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.002B 0.00
Conduit Pharmaceuticals (CDT) United States $0.002B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
Indivior (INDV) United States $0.000B 9.99
4D Pharma (LBPS) United Kingdom $0.000B 0.00
MEI Pharma (MEIP) United States $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00
Silence Therapeutics (SLN) United Kingdom $0.000B 0.00