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Ionis Pharmaceuticals - 10 Year Stock Price History | IONS

Historical daily share price chart and data for Ionis Pharmaceuticals since 2015 adjusted for splits and dividends. The latest closing stock price for Ionis Pharmaceuticals as of March 19, 2025 is 33.34.
  • The all-time high Ionis Pharmaceuticals stock closing price was 86.14 on April 08, 2019.
  • The Ionis Pharmaceuticals 52-week high stock price is 52.34, which is 57% above the current share price.
  • The Ionis Pharmaceuticals 52-week low stock price is 30.23, which is 9.3% below the current share price.
  • The average Ionis Pharmaceuticals stock price for the last 52 weeks is 39.85.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Ionis Pharmaceuticals Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 32.8656 34.6900 34.9700 30.3500 33.3400 -4.63%
2024 43.1007 52.8700 53.5500 33.7300 34.9600 -30.90%
2023 41.3095 37.5800 51.6300 33.5800 50.5900 33.94%
2022 38.7002 32.6000 48.6600 29.8800 37.7700 24.12%
2021 40.8556 56.7800 63.7800 25.6100 30.4300 -46.18%
2020 54.1691 60.8900 63.4000 41.6000 56.5400 -6.41%
2019 64.9707 53.7700 86.1400 52.9200 60.4100 11.75%
2018 48.2372 49.2500 59.5400 40.5250 54.0600 7.48%
2017 49.6931 47.3400 64.3900 37.9100 50.3000 5.16%
2016 35.8627 61.6800 61.6800 20.6200 47.8300 -22.77%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $5.069B $0.705B
Ionis Pharmaceuticals discovers/develops RNA-targeted therapeutics using its proprietary antisense oligonucleotide technology. Its antisense medicines have been developed/are being developed to treat neurological, cardiovascular and specialty rare diseases.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $83.625B 33.00
Zoetis (ZTS) United States $74.024B 27.92
Takeda Pharmaceutical (TAK) Japan $44.801B 9.92
Daiichi Sankyo, - (DSNKY) Japan $43.243B 26.35
Sandoz Group AG (SDZNY) Switzerland $20.284B 0.00
Merck (MKKGY) Germany $18.475B 16.55
Astellas Pharma (ALPMY) Japan $17.608B 12.47
United Therapeutics (UTHR) United States $15.992B 15.73
Summit Therapeutics (SMMT) United States $13.894B 0.00
Shionogi (SGIOY) Japan $12.709B 12.73
Neurocrine Biosciences (NBIX) United States $11.876B 36.20
Orion OYJ (ORINY) Finland $7.630B 21.45
Madrigal Pharmaceuticals (MDGL) United States $7.026B 0.00
Corcept Therapeutics (CORT) United States $6.476B 49.06
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.416B 0.00
Stevanato Group S.p.A (STVN) Italy $6.396B 41.41
Grifols, S.A (GRFS) Spain $5.109B 0.00
Ono Pharmaceutical (OPHLF) Japan $4.650B 9.52
Recursion Pharmaceuticals (RXRX) United States $3.517B 0.00
Crinetics Pharmaceuticals (CRNX) United States $3.211B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.572B 15.37
Catalyst Pharmaceuticals (CPRX) United States $2.535B 11.49
Hypermarcas (HYPMY) Brazil $2.065B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $2.065B 0.00
Soleno Therapeutics (SLNO) United States $1.941B 0.00
BioCryst Pharmaceuticals (BCRX) United States $1.717B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $1.620B 0.00
Evotec AG (EVO) Germany $1.581B 0.00
Dyne Therapeutics (DYN) United States $1.383B 0.00
Guardian Pharmacy Services (GRDN) United States $1.264B 0.00
Ardelyx (ARDX) United States $1.223B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.153B 0.00
Indivior (INDV) United States $1.138B 4.94
Ocular Therapeutix (OCUL) United States $1.058B 0.00
Xencor (XNCR) United States $1.054B 0.00
ARS Pharmaceuticals (SPRY) United States $1.053B 0.00
Enliven Therapeutics (ELVN) United States $1.043B 0.00
Harrow (HROW) United States $0.982B 0.00
Collegium Pharmaceutical (COLL) United States $0.941B 5.14
Bioventus (BVS) United States $0.814B 25.72
Avadel Pharmaceuticals (AVDL) Ireland $0.795B 0.00
Cronos Group (CRON) Canada $0.734B 0.00
Relay Therapeutics (RLAY) United States $0.649B 0.00
USANA Health Sciences (USNA) United States $0.623B 11.55
Verve Therapeutics (VERV) United States $0.595B 0.00
Xeris Biopharma Holdings (XERS) United States $0.561B 0.00
Elite Pharmaceuticals (ELTP) United States $0.526B 0.00
OmniAb (OABI) United States $0.514B 0.00
KalVista Pharmaceuticals (KALV) United States $0.511B 0.00
Savara (SVRA) United States $0.455B 0.00
CytoDyn (CYDY) United States $0.440B 0.00
ProKidney (PROK) United States $0.437B 0.00
Theravance Biopharma (TBPH) Cayman Islands $0.436B 0.00
Altimmune (ALT) United States $0.435B 0.00
Siga Technologies (SIGA) United States $0.406B 4.74
Organogenesis (ORGO) United States $0.400B 0.00
Zevra Therapeutics (ZVRA) United States $0.398B 0.00
Aldeyra Therapeutics (ALDX) United States $0.387B 0.00
Akebia Therapeutics (AKBA) United States $0.386B 0.00
Oruka Therapeutics (ORKA) United States $0.380B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.377B 152.79
Esperion Therapeutics (ESPR) United States $0.359B 0.00
Tourmaline Bio (TRML) United States $0.314B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.288B 0.00
Aquestive Therapeutics (AQST) United States $0.270B 0.00
Heron Therapeutics (HRTX) United States $0.269B 0.00
Nature's Sunshine Products (NATR) United States $0.255B 15.19
Avita Medical (RCEL) United States $0.247B 0.00
Innate Pharma SA (IPHYF) France $0.243B 0.00
Korro Bio (KRRO) United States $0.239B 0.00
Profound Medical (PROF) Canada $0.224B 0.00
4D Molecular Therapeutics (FDMT) United States $0.209B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.206B 0.00
Lyell Immunopharma (LYEL) United States $0.194B 0.00
MediWound (MDWD) Israel $0.194B 0.00
Larimar Therapeutics (LRMR) United States $0.193B 0.00
Nanobiotix S.A (NBTX) France $0.182B 0.00
Enanta Pharmaceuticals (ENTA) United States $0.178B 0.00
Inhibikase Therapeutics (IKT) United States $0.172B 0.00
Acrivon Therapeutics (ACRV) United States $0.168B 0.00
Nektar Therapeutics (NKTR) United States $0.156B 0.00
Aclaris Therapeutics (ACRS) United States $0.148B 0.00
Silence Therapeutics (SLN) United Kingdom $0.146B 0.00
Inotiv (NOTV) United States $0.137B 0.00
Champions Oncology (CSBR) United States $0.129B 0.00
Telomir Pharmaceuticals (TELO) United States $0.126B 0.00
Lexeo Therapeutics (LXEO) United States $0.123B 0.00
Cassava Sciences (SAVA) United States $0.120B 0.00
Procaps Group, S.A (PROCF) Luxembourg $0.120B 0.00
ElectroCore (ECOR) United States $0.115B 0.00
VAXART, INC (VXRT) United States $0.115B 0.00
Journey Medical (DERM) United States $0.112B 0.00
Achieve Life Sciences (ACHV) Canada $0.108B 0.00
Cardiol Therapeutics (CRDL) Canada $0.097B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.092B 0.00
Galectin Therapeutics (GALT) United States $0.092B 0.00
Arch Biopartners (ACHFF) Canada $0.087B 0.00
Metagenomi (MGX) United States $0.087B 0.00
Regulus Therapeutics (RGLS) United States $0.085B 0.00
Nutriband (NTRB) United States $0.084B 0.00
Avalo Therapeutics (AVTX) United States $0.084B 0.00
ESSA Pharma (EPIX) Canada $0.076B 0.00
Assertio Holdings (ASRT) United States $0.076B 19.92
Karyopharm Therapeutics (KPTI) United States $0.075B 0.00
PMV Pharmaceuticals (PMVP) United States $0.074B 0.00
Protara Therapeutics (TARA) United States $0.074B 0.00
Pyxis Oncology (PYXS) United States $0.073B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.071B 0.00
Fractyl Health (GUTS) United States $0.068B 0.00
Vivani Medical (VANI) United States $0.068B 0.00
Mural Oncology (MURA) Ireland $0.066B 0.00
Context Therapeutics (CNTX) United States $0.062B 0.00
Century Therapeutics (IPSC) United States $0.061B 0.00
AleAnna (ANNA) United States $0.060B 0.00
Unicycive Therapeutics (UNCY) United States $0.059B 0.00
FibroGen (FGEN) United States $0.058B 0.00
OptiNose (OPTN) United States $0.057B 0.00
Gain Therapeutics (GANX) United States $0.055B 0.00
AlloVir (ALVR) United States $0.051B 0.00
Iterum Therapeutics (ITRM) Ireland $0.050B 0.00
Rafael Holdings (RFL) United States $0.049B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.049B 0.00
Dominari Holdings (DOMH) United States $0.048B 0.00
Prelude Therapeutics (PRLD) United States $0.046B 0.00
VYNE Therapeutics (VYNE) United States $0.041B 0.00
NRx Pharmaceuticals (NRXP) United States $0.040B 0.00
SCYNEXIS (SCYX) United States $0.039B 0.00
Tempest Therapeutics (TPST) United States $0.038B 0.00
CASI Pharmaceuticals (CASI) China $0.037B 0.00
Surrozen (SRZN) United States $0.037B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.031B 0.00
PolyPid (PYPD) Israel $0.031B 0.00
Incannex Healthcare (IXHL) Australia $0.027B 0.00
BioVie (BIVI) United States $0.027B 0.00
Jupiter Neurosciences (JUNS) United States $0.026B 0.00
Natural Alternatives (NAII) United States $0.025B 0.00
DURECT (DRRX) United States $0.025B 0.00
Scienture Holdings (SCNX) United States $0.023B 0.00
Enlivex Therapeutics (ENLV) Israel $0.021B 0.00
Mannatech (MTEX) United States $0.021B 0.00
Vivos Therapeutics (VVOS) United States $0.020B 0.00
Carisma Therapeutics (CARM) United States $0.018B 0.00
GlycoMimetics (GLYC) United States $0.018B 0.00
MEI Pharma (MEIP) United States $0.018B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.017B 0.00
Lipocine (LPCN) United States $0.017B 0.00
Tonix Pharmaceuticals Holding (TNXP) United States $0.016B 0.00
Citius Pharmaceuticals (CTXR) United States $0.015B 0.00
Traws Pharma (TRAW) United States $0.015B 0.00
Biomerica (BMRA) United States $0.014B 0.00
Lyra Therapeutics (LYRA) United States $0.014B 0.00
Cosmos Health (COSM) United States $0.013B 0.00
ProPhase Labs (PRPH) United States $0.013B 0.00
Minerva Neurosciences (NERV) United States $0.013B 0.00
BioLineRx (BLRX) Israel $0.012B 0.00
Nuvilex (PMCB) United States $0.012B 0.00
TherapeuticsMD (TXMD) United States $0.012B 0.00
Mangoceuticals (MGRX) United States $0.011B 0.00
Indaptus Therapeutics (INDP) United States $0.011B 0.00
Phio Pharmaceuticals (PHIO) United States $0.011B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.010B 0.00
Klotho Neurosciences (KLTO) United States $0.010B 0.00
Addex Therapeutics (ADXN) Switzerland $0.010B 0.00
Talphera (TLPH) United States $0.009B 0.00
Jaguar Animal Health (JAGX) United States $0.009B 0.00
Ainos (AIMD) United States $0.009B 0.00
Relmada Therapeutics (RLMD) United States $0.009B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.008B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.007B 0.00
Plus Therapeutics (PSTV) United States $0.007B 0.00
Redhill Biopharma (RDHL) Israel $0.006B 0.00
Xenetic Biosciences (XBIO) United States $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.005B 0.00
Clearmind Medicine (CMND) Canada $0.005B 0.00
CERo Therapeutics Holdings (CERO) United States $0.005B 0.00
TransCode Therapeutics (RNAZ) United States $0.005B 0.00
Conduit Pharmaceuticals (CDT) United States $0.004B 0.00
SciSparc (SPRC) Israel $0.004B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.004B 0.00
InMed Pharmaceuticals (INM) Canada $0.004B 0.00
China SXT Pharmaceuticals (SXTC) China $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.003B 0.00
Avenue Therapeutics (ATXI) United States $0.003B 0.07
Alaunos Therapeutics (TCRT) United States $0.003B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.002B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.002B 0.00
SHINECO (SISI) China $0.002B 0.00
Heatwurx (PCSA) United States $0.002B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.002B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.002B 0.00
Petros Pharmaceuticals (PTPI) United States $0.001B 0.00
Aditxt (ADTX) United States $0.001B 0.00
TNF Pharmaceuticals (TNFA) United States $0.001B 0.00
PainReform (PRFX) Israel $0.000B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
4D Pharma (LBPS) United Kingdom $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00