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Karyopharm Therapeutics - 12 Year Stock Price History | KPTI

Historical daily share price chart and data for Karyopharm Therapeutics since 2013 adjusted for splits and dividends. The latest closing stock price for Karyopharm Therapeutics as of June 09, 2025 is 4.21.
  • The all-time high Karyopharm Therapeutics stock closing price was 706.80 on June 13, 2014.
  • The Karyopharm Therapeutics 52-week high stock price is 17.39, which is 313.1% above the current share price.
  • The Karyopharm Therapeutics 52-week low stock price is 3.51, which is 16.6% below the current share price.
  • The average Karyopharm Therapeutics stock price for the last 52 weeks is 10.08.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Karyopharm Therapeutics Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 6.9854 12.1740 12.4350 3.5400 4.2100 -58.50%
2024 14.6075 13.5180 24.9000 8.9250 10.1445 -21.82%
2023 31.9730 48.9000 68.8500 10.1370 12.9750 -74.56%
2022 89.8874 106.5000 215.7000 37.2000 51.0000 -47.12%
2021 138.9610 253.8000 265.3500 66.7500 96.4500 -58.46%
2020 261.7355 280.8000 415.8000 212.1000 232.2000 -19.25%
2019 136.4331 143.4000 294.9750 61.8000 287.5500 104.59%
2018 223.2481 148.8000 317.7000 123.0000 140.5500 -2.40%
2017 153.0592 144.6000 207.6000 121.8000 144.0000 2.13%
2016 124.0330 201.9000 205.5000 79.9500 141.0000 -29.06%
2015 335.3277 569.8500 569.8500 155.5500 198.7500 -64.60%
2014 526.6548 345.1500 706.8000 323.5500 561.4500 63.31%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.036B $0.145B
Karyopharm Therapeutics, Inc. is a clinical-stage pharmaceutical company focused on the discovery and development of drugs for the treatment of cancer and other major diseases. It serves the healthcare industry throughout the United States. Karyopharm Therapeutics, Inc. is based in United States.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $88.413B 33.17
Zoetis (ZTS) United States $73.286B 27.34
Takeda Pharmaceutical (TAK) Japan $47.888B 9.53
Daiichi Sankyo, - (DSNKY) Japan $46.809B 23.99
BeOne Medicines - (ONC) Cayman Islands $28.882B 0.00
Sandoz Group AG (SDZNY) Switzerland $23.527B 0.00
Merck (MKKGY) Germany $17.002B 12.46
Summit Therapeutics (SMMT) United States $16.012B 0.00
United Therapeutics (UTHR) United States $14.813B 13.10
Shionogi (SGIOY) Japan $14.530B 14.56
Neurocrine Biosciences (NBIX) United States $12.443B 42.62
Orion OYJ (ORINY) Finland $10.083B 27.27
IPSEN (IPSEY) France $9.974B 0.00
Corcept Therapeutics (CORT) United States $7.484B 60.84
Stevanato Group S.p.A (STVN) Italy $7.071B 43.24
Madrigal Pharmaceuticals (MDGL) United States $6.222B 0.00
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.153B 0.00
Grifols, S.A (GRFS) Spain $6.071B 0.00
Ionis Pharmaceuticals (IONS) United States $5.851B 0.00
Ono Pharmaceutical (OPHLF) Japan $4.980B 15.15
Soleno Therapeutics (SLNO) United States $3.917B 0.00
Catalyst Pharmaceuticals (CPRX) United States $3.152B 11.04
Hypermarcas (HYPMY) Brazil $3.110B 20.46
Crinetics Pharmaceuticals (CRNX) United States $3.022B 0.00
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.385B 12.90
BioCryst Pharmaceuticals (BCRX) United States $2.325B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $2.263B 0.00
Recursion Pharmaceuticals (RXRX) United States $2.183B 0.00
Indivior (INDV) United States $1.852B 7.85
Dyne Therapeutics (DYN) United States $1.637B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $1.595B 0.00
Evotec AG (EVO) Germany $1.463B 0.00
ARS Pharmaceuticals (SPRY) United States $1.427B 0.00
Ocular Therapeutix (OCUL) United States $1.418B 0.00
Guardian Pharmacy Services (GRDN) United States $1.287B 0.00
Harrow (HROW) United States $1.106B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.100B 22.00
Akebia Therapeutics (AKBA) United States $1.006B 0.00
Enliven Therapeutics (ELVN) United States $0.998B 0.00
Collegium Pharmaceutical (COLL) United States $0.978B 5.28
Avadel Pharmaceuticals (AVDL) Ireland $0.974B 0.00
Ardelyx (ARDX) United States $0.900B 0.00
Cronos Group (CRON) Canada $0.756B 0.00
KalVista Pharmaceuticals (KALV) United States $0.734B 0.00
Elite Pharmaceuticals (ELTP) United States $0.725B 0.00
Xeris Biopharma Holdings (XERS) United States $0.701B 0.00
Xencor (XNCR) United States $0.680B 0.00
Liminatus Pharma (LIMN) United States $0.676B 0.00
AleAnna (ANNA) United States $0.589B 0.00
Relay Therapeutics (RLAY) United States $0.576B 0.00
Regulus Therapeutics (RGLS) United States $0.575B 0.00
USANA Health Sciences (USNA) United States $0.555B 12.07
Bioventus (BVS) United States $0.552B 14.00
Theravance Biopharma (TBPH) United States $0.548B 0.00
Verve Therapeutics (VERV) United States $0.544B 0.00
Zevra Therapeutics (ZVRA) United States $0.503B 0.00
Tourmaline Bio (TRML) United States $0.485B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.485B 0.00
Altimmune (ALT) United States $0.483B 0.00
Oruka Therapeutics (ORKA) United States $0.470B 0.00
Organogenesis (ORGO) United States $0.436B 0.00
Siga Technologies (SIGA) United States $0.433B 9.04
Savara (SVRA) United States $0.411B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.391B 10.56
Aquestive Therapeutics (AQST) United States $0.352B 0.00
Heron Therapeutics (HRTX) United States $0.323B 0.00
Tonix Pharmaceuticals Holding (TNXP) United States $0.287B 0.00
ProKidney (PROK) United States $0.287B 0.00
Nature's Sunshine Products (NATR) United States $0.268B 24.73
Esperion Therapeutics (ESPR) United States $0.238B 0.00
MediWound (MDWD) Israel $0.232B 0.00
4D Molecular Therapeutics (FDMT) United States $0.222B 0.00
Nanobiotix S.A (NBTX) France $0.220B 0.00
Lyell Immunopharma (LYEL) United States $0.185B 0.00
OmniAb (OABI) United States $0.183B 0.00
Profound Medical (PROF) Canada $0.173B 0.00
Larimar Therapeutics (LRMR) United States $0.170B 0.00
Journey Medical (DERM) United States $0.167B 0.00
Avita Medical (RCEL) United States $0.162B 0.00
Aclaris Therapeutics (ACRS) United States $0.161B 0.00
Enanta Pharmaceuticals (ENTA) United States $0.160B 0.00
Aldeyra Therapeutics (ALDX) United States $0.160B 0.00
Lexeo Therapeutics (LXEO) United States $0.145B 0.00
Inhibikase Therapeutics (IKT) United States $0.145B 0.00
Fractyl Health (GUTS) United States $0.141B 0.00
Korro Bio (KRRO) United States $0.139B 0.00
Achieve Life Sciences (ACHV) Canada $0.130B 0.00
Wellgistics Health (WGRX) United States $0.126B 0.00
Protara Therapeutics (TARA) United States $0.126B 0.00
Innate Pharma SA (IPHYF) France $0.122B 0.00
Cardiol Therapeutics (CRDL) Canada $0.119B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.113B 0.00
Nektar Therapeutics (NKTR) United States $0.109B 0.00
Unicycive Therapeutics (UNCY) United States $0.109B 0.00
Cassava Sciences (SAVA) United States $0.104B 0.00
Inotiv (NOTV) United States $0.103B 0.00
OptiNose (OPTN) United States $0.097B 0.00
Ironwood Pharmaceuticals (IRWD) United States $0.095B 0.00
Champions Oncology (CSBR) United States $0.091B 15.00
VAXART, INC (VXRT) United States $0.091B 0.00
Arch Biopartners (ACHFF) Canada $0.090B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.088B 65.44
Nutriband (NTRB) United States $0.087B 0.00
Pyxis Oncology (PYXS) United States $0.084B 0.00
Galectin Therapeutics (GALT) United States $0.084B 0.00
Dominari Holdings (DOMH) United States $0.077B 0.00
ESSA Pharma (EPIX) Canada $0.075B 0.00
Surrozen (SRZN) United States $0.075B 0.00
Vivani Medical (VANI) United States $0.068B 0.00
Prelude Therapeutics (PRLD) United States $0.067B 0.00
NRx Pharmaceuticals (NRXP) United States $0.063B 0.00
Context Therapeutics (CNTX) United States $0.063B 0.00
Assertio Holdings (ASRT) United States $0.063B 0.00
Metagenomi (MGX) United States $0.062B 0.00
Telomir Pharmaceuticals (TELO) United States $0.059B 0.00
Allergy Therapeutics (AGYTF) United Kingdom $0.059B 0.00
Gain Therapeutics (GANX) United States $0.057B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.057B 0.00
Rafael Holdings (RFL) United States $0.056B 0.00
PMV Pharmaceuticals (PMVP) United States $0.055B 0.00
Century Therapeutics (IPSC) United States $0.054B 0.00
Avalo Therapeutics (AVTX) United States $0.049B 0.00
Mural Oncology (MURA) Ireland $0.045B 0.00
ElectroCore (ECOR) United States $0.041B 0.00
Iterum Therapeutics (ITRM) Ireland $0.041B 0.00
Acrivon Therapeutics (ACRV) United States $0.040B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.039B 0.00
PolyPid (PYPD) Israel $0.034B 0.00
SCYNEXIS (SCYX) United States $0.034B 0.00
Tempest Therapeutics (TPST) United States $0.033B 0.00
FibroGen (FGEN) United States $0.032B 0.00
China SXT Pharmaceuticals (SXTC) China $0.031B 0.00
Jupiter Neurosciences (JUNS) United States $0.030B 0.00
Relmada Therapeutics (RLMD) United States $0.027B 0.00
Lyra Therapeutics (LYRA) United States $0.024B 0.00
CASI Pharmaceuticals (CASI) China $0.023B 0.00
Enlivex Therapeutics (ENLV) Israel $0.022B 0.00
Natural Alternatives (NAII) United States $0.021B 0.00
BioVie (BIVI) United States $0.021B 0.00
Mannatech (MTEX) United States $0.021B 0.00
BioLineRx (BLRX) Israel $0.020B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.019B 0.00
Lipocine (LPCN) United States $0.018B 0.00
DURECT (DRRX) United States $0.017B 0.00
ProPhase Labs (PRPH) United States $0.015B 0.00
VYNE Therapeutics (VYNE) United States $0.015B 0.00
TherapeuticsMD (TXMD) United States $0.014B 0.00
Scienture Holdings (SCNX) United States $0.014B 0.00
Citius Pharmaceuticals (CTXR) United States $0.014B 0.00
Cosmos Health (COSM) United States $0.014B 0.00
Phio Pharmaceuticals (PHIO) United States $0.013B 0.00
Minerva Neurosciences (NERV) United States $0.013B 2.24
Ainos (AIMD) United States $0.013B 0.00
Vivos Therapeutics (VVOS) United States $0.013B 0.00
Ernexa Therapeutics (ERNA) United States $0.012B 0.00
GlycoMimetics (GLYC) United States $0.011B 0.00
Addex Therapeutics (ADXN) Switzerland $0.011B 0.00
Mangoceuticals (MGRX) United States $0.011B 0.00
Talphera (TLPH) United States $0.011B 0.00
SHINECO (SISI) China $0.010B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.010B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.010B 0.00
Carisma Therapeutics (CARM) United States $0.009B 0.00
Traws Pharma (TRAW) United States $0.009B 0.00
Biomerica (BMRA) United States $0.009B 0.00
Nuvilex (PMCB) United States $0.007B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.007B 0.00
TransCode Therapeutics (RNAZ) United States $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.006B 0.00
Plus Therapeutics (PSTV) United States $0.006B 0.00
Incannex Healthcare (IXHL) Australia $0.006B 0.00
Indaptus Therapeutics (INDP) United States $0.005B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.005B 0.00
Alaunos Therapeutics (TCRT) United States $0.005B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.005B 0.00
Xenetic Biosciences (XBIO) United States $0.005B 0.00
Redhill Biopharma (RDHL) Israel $0.005B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.004B 0.00
Clearmind Medicine (CMND) Canada $0.004B 0.00
PainReform (PRFX) Israel $0.004B 0.00
Jaguar Animal Health (JAGX) United States $0.004B 0.00
Heatwurx (PCSA) United States $0.004B 0.00
SciSparc (SPRC) Israel $0.004B 0.00
InMed Pharmaceuticals (INM) Canada $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
Aditxt (ADTX) United States $0.003B 0.00
CERo Therapeutics Holdings (CERO) United States $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.003B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.003B 0.00
TNF Pharmaceuticals (TNFA) United States $0.002B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.002B 0.00
Conduit Pharmaceuticals (CDT) United States $0.002B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.002B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
Klotho Neurosciences (KLTO) United States $0.000B 0.00
4D Pharma (LBPS) United Kingdom $0.000B 0.00
MEI Pharma (MEIP) United States $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00
Silence Therapeutics (SLN) United Kingdom $0.000B 0.00