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Karyopharm Therapeutics - 12 Year Stock Price History | KPTI

Historical daily share price chart and data for Karyopharm Therapeutics since 2013 adjusted for splits and dividends. The latest closing stock price for Karyopharm Therapeutics as of June 20, 2025 is 4.38.
  • The all-time high Karyopharm Therapeutics stock closing price was 706.80 on June 13, 2014.
  • The Karyopharm Therapeutics 52-week high stock price is 17.39, which is 297% above the current share price.
  • The Karyopharm Therapeutics 52-week low stock price is 3.51, which is 19.9% below the current share price.
  • The average Karyopharm Therapeutics stock price for the last 52 weeks is 9.77.
For more information on how our historical price data is adjusted see the Stock Price Adjustment Guide.
  
Karyopharm Therapeutics Historical Annual Stock Price Data
Year Average Stock Price Year Open Year High Year Low Year Close Annual % Change
2025 6.8080 12.1740 12.4350 3.5400 4.3800 -56.82%
2024 14.6075 13.5180 24.9000 8.9250 10.1445 -21.82%
2023 31.9730 48.9000 68.8500 10.1370 12.9750 -74.56%
2022 89.8874 106.5000 215.7000 37.2000 51.0000 -47.12%
2021 138.9610 253.8000 265.3500 66.7500 96.4500 -58.46%
2020 261.7355 280.8000 415.8000 212.1000 232.2000 -19.25%
2019 136.4331 143.4000 294.9750 61.8000 287.5500 104.59%
2018 223.2481 148.8000 317.7000 123.0000 140.5500 -2.40%
2017 153.0592 144.6000 207.6000 121.8000 144.0000 2.13%
2016 124.0330 201.9000 205.5000 79.9500 141.0000 -29.06%
2015 335.3277 569.8500 569.8500 155.5500 198.7500 -64.60%
2014 526.6548 345.1500 706.8000 323.5500 561.4500 63.31%
Sector Industry Market Cap Revenue
Medical Medical - Drug Manufacturing $0.038B $0.145B
Karyopharm Therapeutics, Inc. is a clinical-stage pharmaceutical company focused on the discovery and development of drugs for the treatment of cancer and other major diseases. It serves the healthcare industry throughout the United States. Karyopharm Therapeutics, Inc. is based in United States.
Stock Name Country Market Cap PE Ratio
Chugai Pharmaceutical (CHGCY) Japan $80.630B 30.25
Zoetis (ZTS) United States $69.973B 26.11
Takeda Pharmaceutical (TAK) Japan $46.997B 9.35
Daiichi Sankyo, - (DSNKY) Japan $42.922B 22.00
BeOne Medicines - (ONC) Cayman Islands $27.070B 0.00
Sandoz Group AG (SDZNY) Switzerland $23.434B 0.00
Merck (MKKGY) Germany $16.421B 12.03
Summit Therapeutics (SMMT) United States $15.269B 0.00
Shionogi (SGIOY) Japan $14.428B 14.45
United Therapeutics (UTHR) United States $13.115B 11.60
Neurocrine Biosciences (NBIX) United States $12.524B 42.90
Orion OYJ (ORINY) Finland $10.594B 28.65
IPSEN (IPSEY) France $9.831B 0.00
Corcept Therapeutics (CORT) United States $7.569B 61.53
Stevanato Group S.p.A (STVN) Italy $7.053B 43.13
Madrigal Pharmaceuticals (MDGL) United States $6.344B 0.00
Hikma Pharmaceuticals Plc (HKMPF) United Kingdom $6.153B 0.00
Grifols, S.A (GRFS) Spain $6.030B 0.00
Ionis Pharmaceuticals (IONS) United States $5.954B 0.00
Ono Pharmaceutical (OPHLF) Japan $5.031B 15.30
Soleno Therapeutics (SLNO) United States $4.031B 0.00
Hypermarcas (HYPMY) Brazil $3.075B 20.23
Crinetics Pharmaceuticals (CRNX) United States $2.824B 0.00
Catalyst Pharmaceuticals (CPRX) United States $2.742B 9.61
AMNEAL PHARMACEUTICALS, INC (AMRX) United States $2.451B 13.25
BioCryst Pharmaceuticals (BCRX) United States $2.113B 0.00
Recursion Pharmaceuticals (RXRX) United States $2.045B 0.00
NewAmsterdam Pharma (NAMS) Netherlands $2.016B 0.00
Centessa Pharmaceuticals (CNTA) United Kingdom $1.660B 0.00
Endo (NDOI) United States $1.595B 0.00
ARS Pharmaceuticals (SPRY) United States $1.552B 0.00
Evotec AG (EVO) Germany $1.335B 0.00
Ocular Therapeutix (OCUL) United States $1.295B 0.00
Guardian Pharmacy Services (GRDN) United States $1.272B 0.00
Dyne Therapeutics (DYN) United States $1.173B 0.00
Harrow (HROW) United States $1.125B 0.00
Aurinia Pharmaceuticals Inc (AUPH) Canada $1.050B 21.00
Enliven Therapeutics (ELVN) United States $1.045B 0.00
Verve Therapeutics (VERV) United States $0.986B 0.00
Akebia Therapeutics (AKBA) United States $0.967B 0.00
Collegium Pharmaceutical (COLL) United States $0.959B 5.17
Avadel Pharmaceuticals (AVDL) Ireland $0.888B 0.00
Ardelyx (ARDX) United States $0.852B 0.00
Elite Pharmaceuticals (ELTP) United States $0.793B 0.00
Cronos Group (CRON) Canada $0.717B 0.00
Xeris Biopharma Holdings (XERS) United States $0.705B 0.00
Xencor (XNCR) United States $0.608B 0.00
KalVista Pharmaceuticals (KALV) United States $0.604B 0.00
Altimmune (ALT) United States $0.570B 0.00
USANA Health Sciences (USNA) United States $0.569B 12.37
Relay Therapeutics (RLAY) United States $0.547B 0.00
Regulus Therapeutics (RGLS) United States $0.546B 0.00
Bioventus (BVS) United States $0.538B 13.65
Theravance Biopharma (TBPH) United States $0.532B 0.00
AleAnna (ANNA) United States $0.504B 0.00
Zevra Therapeutics (ZVRA) United States $0.494B 0.00
Amylyx Pharmaceuticals (AMLX) United States $0.450B 0.00
Oruka Therapeutics (ORKA) United States $0.437B 0.00
Siga Technologies (SIGA) United States $0.437B 9.13
Tourmaline Bio (TRML) United States $0.427B 0.00
Organogenesis (ORGO) United States $0.410B 0.00
Liminatus Pharma (LIMN) United States $0.375B 0.00
Savara (SVRA) United States $0.356B 0.00
Rigel Pharmaceuticals (RIGL) United States $0.338B 9.14
Aquestive Therapeutics (AQST) United States $0.323B 0.00
Heron Therapeutics (HRTX) United States $0.305B 0.00
Nature's Sunshine Products (NATR) United States $0.271B 24.86
Tonix Pharmaceuticals Holding (TNXP) United States $0.238B 0.00
Esperion Therapeutics (ESPR) United States $0.212B 0.00
Nanobiotix S.A (NBTX) France $0.211B 0.00
MediWound (MDWD) Israel $0.206B 0.00
OmniAb (OABI) United States $0.194B 0.00
ProKidney (PROK) United States $0.193B 0.00
4D Molecular Therapeutics (FDMT) United States $0.191B 0.00
Profound Medical (PROF) Canada $0.191B 0.00
Aldeyra Therapeutics (ALDX) United States $0.183B 0.00
Larimar Therapeutics (LRMR) United States $0.166B 0.00
Aclaris Therapeutics (ACRS) United States $0.157B 0.00
Enanta Pharmaceuticals (ENTA) United States $0.153B 0.00
Galectin Therapeutics (GALT) United States $0.153B 0.00
Journey Medical (DERM) United States $0.152B 0.00
Innate Pharma SA (IPHYF) France $0.145B 0.00
Avita Medical (RCEL) United States $0.137B 0.00
VAXART, INC (VXRT) United States $0.132B 0.00
Lexeo Therapeutics (LXEO) United States $0.130B 0.00
Lyell Immunopharma (LYEL) United States $0.129B 0.00
Inhibikase Therapeutics (IKT) United States $0.123B 0.00
Protara Therapeutics (TARA) United States $0.118B 0.00
Achieve Life Sciences (ACHV) Canada $0.116B 0.00
Korro Bio (KRRO) United States $0.116B 0.00
Champions Oncology (CSBR) United States $0.115B 18.84
Ironwood Pharmaceuticals (IRWD) United States $0.114B 0.00
Nektar Therapeutics (NKTR) United States $0.106B 0.00
Fractyl Health (GUTS) United States $0.105B 0.00
Cardiol Therapeutics (CRDL) Canada $0.102B 0.00
Corbus Pharmaceuticals Holdings (CRBP) United States $0.101B 0.00
Cassava Sciences (SAVA) United States $0.096B 0.00
Wellgistics Health (WGRX) United States $0.087B 0.00
Nutriband (NTRB) United States $0.087B 0.00
Surrozen (SRZN) United States $0.086B 0.00
Dominari Holdings (DOMH) United States $0.083B 0.00
Arch Biopartners (ACHFF) Canada $0.083B 0.00
Unicycive Therapeutics (UNCY) United States $0.080B 0.00
ESSA Pharma (EPIX) Canada $0.077B 0.00
Vivani Medical (VANI) United States $0.075B 0.00
Pyxis Oncology (PYXS) United States $0.072B 0.00
Inotiv (NOTV) United States $0.070B 0.00
Cumberland Pharmaceuticals (CPIX) United States $0.065B 48.33
Assertio Holdings (ASRT) United States $0.060B 0.00
Allergy Therapeutics (AGYTF) United Kingdom $0.059B 0.00
PMV Pharmaceuticals (PMVP) United States $0.057B 0.00
NRx Pharmaceuticals (NRXP) United States $0.056B 0.00
Rafael Holdings (RFL) United States $0.055B 0.00
Metagenomi (MGX) United States $0.054B 0.00
Verrica Pharmaceuticals (VRCA) United States $0.054B 0.00
Gain Therapeutics (GANX) United States $0.053B 0.00
Telomir Pharmaceuticals (TELO) United States $0.052B 0.00
Context Therapeutics (CNTX) United States $0.051B 0.00
Avalo Therapeutics (AVTX) United States $0.050B 0.00
Century Therapeutics (IPSC) United States $0.050B 0.00
Klotho Neurosciences (KLTO) United States $0.050B 0.00
Prelude Therapeutics (PRLD) United States $0.049B 0.00
Mural Oncology (MURA) Ireland $0.042B 0.00
Iterum Therapeutics (ITRM) Ireland $0.040B 0.00
ElectroCore (ECOR) United States $0.038B 0.00
Acrivon Therapeutics (ACRV) United States $0.037B 0.00
Jupiter Neurosciences (JUNS) United States $0.037B 0.00
PolyPid (PYPD) Israel $0.033B 0.00
Reviva Pharmaceuticals Holdings (RVPH) United States $0.033B 0.00
China SXT Pharmaceuticals (SXTC) China $0.029B 0.00
SCYNEXIS (SCYX) United States $0.029B 0.00
Enlivex Therapeutics (ENLV) Israel $0.026B 0.00
Tempest Therapeutics (TPST) United States $0.025B 0.00
FibroGen (FGEN) United States $0.023B 0.00
Relmada Therapeutics (RLMD) United States $0.023B 0.00
DURECT (DRRX) United States $0.021B 0.00
Natural Alternatives (NAII) United States $0.020B 0.00
BioVie (BIVI) United States $0.019B 0.00
Mannatech (MTEX) United States $0.019B 0.00
Carisma Therapeutics (CARM) United States $0.018B 0.00
BioLineRx (BLRX) Israel $0.018B 0.00
Ernexa Therapeutics (ERNA) United States $0.018B 0.00
Lipocine (LPCN) United States $0.018B 0.00
Vivos Therapeutics (VVOS) United States $0.016B 0.00
MARKER THERAPEUTICS, INC (MRKR) United States $0.016B 0.00
CASI Pharmaceuticals (CASI) China $0.016B 0.00
ProPhase Labs (PRPH) United States $0.014B 0.00
Lyra Therapeutics (LYRA) United States $0.014B 0.00
VYNE Therapeutics (VYNE) United States $0.014B 0.00
TherapeuticsMD (TXMD) United States $0.013B 0.00
Cosmos Health (COSM) United States $0.012B 0.00
Minerva Neurosciences (NERV) United States $0.012B 2.16
Scienture Holdings (SCNX) United States $0.012B 0.00
Citius Pharmaceuticals (CTXR) United States $0.011B 0.00
Phio Pharmaceuticals (PHIO) United States $0.011B 0.00
Mangoceuticals (MGRX) United States $0.011B 0.00
Ainos (AIMD) United States $0.010B 0.00
Kiora Pharmaceuticals (KPRX) United States $0.010B 0.00
Talphera (TLPH) United States $0.009B 0.00
Traws Pharma (TRAW) United States $0.009B 0.00
Addex Therapeutics (ADXN) Switzerland $0.009B 0.00
NLS Pharmaceutics (NLSP) Switzerland $0.009B 0.00
Biomerica (BMRA) United States $0.008B 0.00
Nuvilex (PMCB) United States $0.007B 0.00
Alaunos Therapeutics (TCRT) United States $0.007B 0.00
SHINECO (SISI) China $0.007B 0.00
Incannex Healthcare (IXHL) Australia $0.006B 0.00
TransCode Therapeutics (RNAZ) United States $0.006B 0.00
Aptorum Group (APM) United Kingdom $0.005B 0.00
XTL Biopharmaceuticals (XTLB) Israel $0.005B 0.00
Quoin Pharmaceuticals (QNRX) United States $0.005B 0.00
Sonoma Pharmaceuticals (SNOA) United States $0.005B 0.00
Redhill Biopharma (RDHL) Israel $0.004B 0.00
Indaptus Therapeutics (INDP) United States $0.004B 0.00
Xenetic Biosciences (XBIO) United States $0.004B 0.00
CERo Therapeutics Holdings (CERO) United States $0.004B 0.00
Heatwurx (PCSA) United States $0.004B 0.00
Clearmind Medicine (CMND) Canada $0.004B 0.00
SciSparc (SPRC) Israel $0.003B 0.00
XORTX Therapeutics (XRTX) Canada $0.003B 0.00
Plus Therapeutics (PSTV) United States $0.003B 0.00
PainReform (PRFX) Israel $0.003B 0.00
Galmed Pharmaceuticals (GLMD) Israel $0.003B 0.00
60 Degrees Pharmaceuticals (SXTP) United States $0.003B 0.00
InMed Pharmaceuticals (INM) Canada $0.003B 0.00
Jaguar Animal Health (JAGX) United States $0.003B 0.00
Aditxt (ADTX) United States $0.003B 0.00
Qualigen Therapeutics (QLGN) United States $0.003B 0.00
Salarius Pharmaceuticals (SLRX) United States $0.002B 0.00
TNF Pharmaceuticals (TNFA) United States $0.002B 0.00
Conduit Pharmaceuticals (CDT) United States $0.002B 0.00
Shuttle Pharmaceuticals Holdings (SHPH) United States $0.002B 0.00
Universe Pharmaceuticals INC (UPC) China $0.000B 0.00
Indivior (INDV) United States $0.000B 8.19
4D Pharma (LBPS) United Kingdom $0.000B 0.00
MEI Pharma (MEIP) United States $0.000B 0.00
Patheon (PTHN) Netherlands $0.000B 0.00
RVL Pharmaceuticals (RVLP) United States $0.000B 0.00
Silence Therapeutics (SLN) United Kingdom $0.000B 0.00