Ono Pharmaceutical Operating Income 2012-2025 | OPHLF

Ono Pharmaceutical annual/quarterly operating income history and growth rate from 2012 to 2025. Operating income can be defined as income after operating expenses have been deducted and before interest payments and taxes have been deducted.

Ono Pharmaceutical operating income for the quarter ending September 30, 2025 was $0M, a 100% decline year-over-year.
Ono Pharmaceutical operating income for the twelve months ending September 30, 2025 was $0.650B, a 34.89% decline year-over-year.
Ono Pharmaceutical annual operating income for 2025 was $0.394B, a 64.27% decline from 2024.
Ono Pharmaceutical annual operating income for 2024 was $1.104B, a 5.05% increase from 2023.
Ono Pharmaceutical annual operating income for 2023 was $1.051B, a 14.38% increase from 2022.

Ono Pharmaceutical Annual Operating Income (Millions of US $)
2025	$394
2024	$1,104
2023	$1,051
2022	$918
2021	$924
2020	$713
2019	$558
2018	$572
2017	$645
2016	$272
2015	$123
2014	$272
2013	$340
2012	$462
2011	$1,630

Ono Pharmaceutical Quarterly Operating Income (Millions of US $)
2025-09-30
2025-06-30	$152
2024-06-30	$196
2023-06-30	$302
2022-06-30	$294
2021-06-30	$271
2020-06-30	$252
2019-06-30	$182
2018-06-30	$165
2017-06-30	$127
2016-06-30	$169
2016-03-31	$-468
2015-12-31	$346
2015-09-30	$298
2015-06-30	$96
2015-03-31	$238
2014-12-31	$322
2014-09-30	$257
2014-06-30	$28
2014-03-31	$329
2013-12-31	$344
2013-09-30	$349
2013-06-30	$82
2013-03-31	$255
2012-12-31	$380
2012-09-30	$441
2012-06-30	$151
2012-03-31	$313
2011-12-31	$541
2011-06-30	$454
2011-03-31

Sector	Industry	Market Cap	Revenue
Medical	Medical - Drug Manufacturing	$6.967B	$3.197B
Ono Pharmaceuticals produces, purchases and sells pharmaceuticals and diagnostic reagents focusing primarily on prescription pharmaceuticals.

Stock Name	Country	Market Cap	PE Ratio
Chugai Pharmaceutical (CHGCY)	Japan	$86.784B	32.96
Zoetis (ZTS)	United States	$55.122B	19.73
Takeda Pharmaceutical (TAK)	Japan	$51.166B	10.44
Daiichi Sankyo, - (DSNKY)	Japan	$38.417B	19.13
BeOne Medicines - (ONC)	Switzerland	$37.465B	198.63
Sandoz Group AG (SDZNY)	Switzerland	$34.412B	0.00
United Therapeutics (UTHR)	United States	$20.227B	17.80
Merck (MKKGY)	Germany	$18.999B	11.71
Shionogi (SGIOY)	Japan	$15.585B	14.31
Neurocrine Biosciences (NBIX)	United States	$13.501B	32.40
IPSEN (IPSEY)	France	$13.099B	0.00
Summit Therapeutics (SMMT)	United States	$12.994B	0.00
Ionis Pharmaceuticals (IONS)	United States	$12.867B	0.00
Madrigal Pharmaceuticals (MDGL)	United States	$11.287B	0.00
Orion OYJ (ORINY)	Finland	$10.204B	29.15
Eisai (ESAIY)		$8.190B	0.00
Grifols, S.A (GRFS)	Spain	$6.202B	0.00
Stevanato Group S.p.A (STVN)	Italy	$5.887B	32.95
Crinetics Pharmaceuticals (CRNX)	United States	$5.258B	0.00
Hikma Pharmaceuticals Plc (HKMPF)	United Kingdom	$4.547B	0.00
AMNEAL PHARMACEUTICALS, INC (AMRX)	United States	$4.310B	20.46
Indivior (INDV)	United States	$4.123B	16.83
NewAmsterdam Pharma (NAMS)	Netherlands	$3.848B	0.00
Corcept Therapeutics (CORT)	United States	$3.819B	41.26
Centessa Pharmaceuticals (CNTA)	United Kingdom	$3.123B	0.00
Catalyst Pharmaceuticals (CPRX)	United States	$2.966B	9.46
Hypermarcas (HYPMY)	Brazil	$2.906B	19.95
Dyne Therapeutics (DYN)	United States	$2.499B	0.00
Ocular Therapeutix (OCUL)	United States	$2.433B	0.00
Soleno Therapeutics (SLNO)	United States	$2.340B	0.00
Avadel Pharmaceuticals (AVDL)	Ireland	$2.101B	0.00
Aurinia Pharmaceuticals Inc (AUPH)	Canada	$1.949B	23.09
Ardelyx (ARDX)	United States	$1.941B	0.00
Guardian Pharmacy Services (GRDN)	United States	$1.858B	35.79
Amylyx Pharmaceuticals (AMLX)	United States	$1.858B	0.00
Harrow (HROW)	United States	$1.745B	107.09
Oruka Therapeutics (ORKA)	United States	$1.668B	0.00
Enliven Therapeutics (ELVN)	United States	$1.615B	0.00
Collegium Pharmaceutical (COLL)	United States	$1.486B	7.36
BioCryst Pharmaceuticals (BCRX)	United States	$1.416B	84.00
Relay Therapeutics (RLAY)	United States	$1.307B	0.00
Xeris Biopharma Holdings (XERS)	United States	$1.264B	0.00
Savara (SVRA)	United States	$1.259B	0.00
Evotec AG (EVO)	Germany	$1.243B	0.00
Aktis Oncology (AKTS)	United States	$1.033B	0.00
Theravance Biopharma (TBPH)	United States	$1.032B	43.34
ARS Pharmaceuticals (SPRY)	United States	$1.032B	0.00
Cronos Group (CRON)	Canada	$0.996B	0.00
Xencor (XNCR)	United States	$0.928B	0.00
Ironwood Pharmaceuticals (IRWD)	United States	$0.864B	20.42
KalVista Pharmaceuticals (KALV)	United States	$0.804B	0.00
Nektar Therapeutics (NKTR)	United States	$0.751B	0.00
Esperion Therapeutics (ESPR)	United States	$0.712B	0.00
Rigel Pharmaceuticals (RIGL)	United States	$0.683B	6.10
Bioventus (BVS)	United States	$0.662B	13.56
ProKidney (PROK)	United States	$0.647B	0.00
Lexeo Therapeutics (LXEO)	United States	$0.528B	0.00
Lyell Immunopharma (LYEL)	United States	$0.512B	0.00
Zevra Therapeutics (ZVRA)	United States	$0.508B	0.00
Elite Pharmaceuticals (ELTP)	United States	$0.506B	0.00
Organogenesis (ORGO)	United States	$0.487B	0.00
Altimmune (ALT)	United States	$0.482B	0.00
Aclaris Therapeutics (ACRS)	United States	$0.479B	0.00
Siga Technologies (SIGA)	United States	$0.477B	6.53
4D Molecular Therapeutics (FDMT)	United States	$0.439B	0.00
Nature's Sunshine Products (NATR)	United States	$0.424B	25.24
Aquestive Therapeutics (AQST)	United States	$0.410B	0.00
USANA Health Sciences (USNA)	United States	$0.407B	11.35
Cybin (HELP)	Canada	$0.377B	0.00
Akebia Therapeutics (AKBA)	United States	$0.364B	0.00
Aldeyra Therapeutics (ALDX)	United States	$0.300B	0.00
Protara Therapeutics (TARA)	United States	$0.298B	0.00
Avalo Therapeutics (AVTX)	United States	$0.292B	0.00
Profound Medical (PROF)	Canada	$0.290B	0.00
OmniAb (OABI)	United States	$0.289B	0.00
Achieve Life Sciences (ACHV)	Canada	$0.289B	0.00
Relmada Therapeutics (RLMD)	United States	$0.279B	0.00
Larimar Therapeutics (LRMR)	United States	$0.275B	0.00
Silence Therapeutics (SLN)	United Kingdom	$0.268B	0.00
Heron Therapeutics (HRTX)	United States	$0.268B	0.00
Fractyl Health (GUTS)	United States	$0.254B	0.00
Journey Medical (DERM)	United States	$0.241B	0.00
Enlivex Therapeutics (ENLV)	Israel	$0.233B	0.00
Tonix Pharmaceuticals Holding (TNXP)	United States	$0.221B	0.00
MediWound (MDWD)	Israel	$0.219B	0.00
Galectin Therapeutics (GALT)	United States	$0.204B	0.00
AleAnna (ANNA)	United States	$0.189B	0.00
Minerva Neurosciences (NERV)	United States	$0.181B	0.00
Innate Pharma SA (IPHYF)	France	$0.181B	0.00
Century Therapeutics (IPSC)	United States	$0.178B	0.00
Surrozen (SRZN)	United States	$0.164B	0.00
Procaps Group, S.A (PROCF)	Luxembourg	$0.161B	0.00
VAXART, INC (VXRT)	United States	$0.159B	0.00
Corbus Pharmaceuticals Holdings (CRBP)	United States	$0.152B	0.00
Context Therapeutics (CNTX)	United States	$0.151B	0.00
Unicycive Therapeutics (UNCY)	United States	$0.142B	0.00
Inhibikase Therapeutics (IKT)	United States	$0.132B	0.00
Verrica Pharmaceuticals (VRCA)	United States	$0.124B	0.00
Incannex Healthcare (IXHL)	Australia	$0.123B	0.00
Avita Medical (RCEL)	United States	$0.119B	0.00
Karyopharm Therapeutics (KPTI)	United States	$0.116B	0.00
Prelude Therapeutics (PRLD)	United States	$0.114B	0.00
Vivani Medical (VANI)	United States	$0.110B	0.00
Cassava Sciences (SAVA)	United States	$0.105B	0.00
Pyxis Oncology (PYXS)	United States	$0.103B	0.00
Cardiol Therapeutics (CRDL)	Canada	$0.102B	0.00
Champions Oncology (CSBR)	United States	$0.098B	41.71
Korro Bio (KRRO)	United States	$0.089B	0.00
Gain Therapeutics (GANX)	United States	$0.076B	0.00
Assertio Holdings (ASRT)	United States	$0.074B	0.00
PolyPid (PYPD)	Israel	$0.073B	0.00
NRx Pharmaceuticals (NRXP)	United States	$0.067B	0.00
Acrivon Therapeutics (ACRV)	United States	$0.066B	0.00
Dominari Holdings (DOMH)	United States	$0.066B	0.00
Cumberland Pharmaceuticals (CPIX)	United States	$0.066B	54.75
Rafael Holdings (RFL)	United States	$0.062B	0.00
Metagenomi Therapeutics (MGX)	United States	$0.061B	0.00
ElectroCore (ECOR)	United States	$0.061B	0.00
Arch Biopartners (ACHFF)	Canada	$0.060B	0.00
PMV Pharmaceuticals (PMVP)	United States	$0.056B	0.00
Nutriband (NTRB)	United States	$0.054B	0.00
Lipocine (LPCN)	United States	$0.054B	0.00
Lite Strategy (LITS)	United States	$0.049B	0.00
Talphera (TLPH)	United States	$0.047B	0.00
Telomir Pharmaceuticals (TELO)	United States	$0.045B	0.00
Plus Therapeutics (PSTV)	United States	$0.041B	0.00
FibroGen (FGEN)	United States	$0.039B	0.00
Reviva Pharmaceuticals Holdings (RVPH)	United States	$0.038B	0.00
MARKER THERAPEUTICS, INC (MRKR)	United States	$0.037B	0.00
Wellgistics Health (WGRX)	United States	$0.036B	0.00
Mural Oncology (MURA)	Ireland	$0.035B	0.00
Jupiter Neurosciences (JUNS)	United States	$0.032B	0.00
TherapeuticsMD (TXMD)	United States	$0.029B	0.00
SCYNEXIS (SCYX)	United States	$0.028B	0.00
Natural Alternatives (NAII)	United States	$0.027B	0.00
Klotho Neurosciences (KLTO)	United States	$0.024B	0.00
Scienture Holdings (SCNX)	United States	$0.021B	0.00
Cosmos Health (COSM)	United States	$0.019B	0.00
Traws Pharma (TRAW)	United States	$0.019B	0.02
Liminatus Pharma (LIMN)	United States	$0.019B	0.00
VYNE Therapeutics (VYNE)	United States	$0.019B	0.00
Inotiv (NOTV)	United States	$0.019B	0.00
Vivos Therapeutics (VVOS)	United States	$0.017B	0.00
Iterum Therapeutics (ITRM)	Ireland	$0.017B	0.00
Citius Pharmaceuticals (CTXR)	United States	$0.017B	0.00
Vyome Holdings (HIND)	United States	$0.015B	0.00
Mannatech (MTEX)	United States	$0.014B	0.00
Tempest Therapeutics (TPST)	United States	$0.013B	0.00
BioLineRx (BLRX)	Israel	$0.012B	0.00
CASI Pharmaceuticals (CASI)	China	$0.012B	0.00
Phio Pharmaceuticals (PHIO)	United States	$0.011B	0.00
China SXT Pharmaceuticals (SXTC)	China	$0.011B	0.00
Curanex Pharmaceuticals Inc (CURX)	United States	$0.010B	0.00
Addex Therapeutics (ADXN)	Switzerland	$0.010B	0.00
Ernexa Therapeutics (ERNA)	United States	$0.009B	0.00
BioVie (BIVI)	United States	$0.009B	0.00
Mangoceuticals (MGRX)	United States	$0.009B	0.00
Ainos (AIMD)	United States	$0.009B	0.00
Nuvilex (PMCB)	United States	$0.009B	0.00
TransCode Therapeutics (RNAZ)	United States	$0.009B	0.00
XTL Biopharmaceuticals (XTLB)	Israel	$0.009B	0.00
Quoin Pharmaceuticals (QNRX)	United States	$0.008B	0.00
Kiora Pharmaceuticals (KPRX)	United States	$0.008B	0.00
Biomerica (BMRA)	United States	$0.007B	0.00
Heatwurx (PCSA)	United States	$0.007B	0.00
Alaunos Therapeutics (TCRT)	United States	$0.007B	0.00
Redhill Biopharma (RDHL)	Israel	$0.007B	0.00
Aptorum Group (APM)	United Kingdom	$0.006B	0.00
Indaptus Therapeutics (INDP)	United States	$0.006B	0.00
Sonoma Pharmaceuticals (SNOA)	United States	$0.006B	0.00
Xenetic Biosciences (XBIO)	United States	$0.006B	0.00
Salarius Pharmaceuticals (SLRX)	United States	$0.005B	0.00
XORTX Therapeutics (XRTX)	Canada	$0.004B	0.00
Lyra Therapeutics (LYRA)	United States	$0.004B	0.00
Clearmind Medicine (CMND)	Canada	$0.004B	0.00
Shuttle Pharmaceuticals Holdings (SHPH)	United States	$0.003B	0.00
InMed Pharmaceuticals (INM)	Canada	$0.003B	0.00
Jaguar Animal Health (JAGX)	United States	$0.003B	0.00
CDT Equity (CDT)	United States	$0.002B	0.00
Universe Pharmaceuticals INC (UPC)	China	$0.002B	0.00
60 Degrees Pharmaceuticals (SXTP)	United States	$0.002B	0.00
PainReform (PRFX)	Israel	$0.002B	0.00
Galmed Pharmaceuticals (GLMD)	Israel	$0.001B	0.00
Aditxt (ADTX)	United States	$0.001B	0.00
SciSparc (SPRC)	Israel	$0.001B	0.00
Emisphere Technologies (EMIS)	United States	$0.000B	0.00
4D Pharma (LBPS)	United Kingdom	$0.000B	0.00
Patheon (PTHN)	Netherlands	$0.000B	0.00
RVL Pharmaceuticals (RVLP)	United States	$0.000B	0.00