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Cyclerion Therapeutics Price to Book Ratio 2018-2025 | CYCN

Historical price to book ratio values for Cyclerion Therapeutics (CYCN) over the last 10 years. The current price to book ratio for Cyclerion Therapeutics as of November 13, 2025 is 0.53.

Please refer to the Stock Price Adjustment Guide for more information on our historical prices.
Cyclerion Therapeutics Price/Book Ratio Historical Data
Date Stock Price Book Value per Share Price to Book Ratio
2025-11-13 1.44 0.52
2025-06-30 2.91 $2.79 1.04
2025-03-31 2.50 $2.87 0.87
2024-12-31 3.22 $3.48 0.93
2024-09-30 2.59 $3.24 0.80
2024-06-30 2.30 $3.49 0.66
2024-03-31 3.20 $3.97 0.81
2023-12-31 3.35 $4.56 0.73
2023-09-30 3.42 $5.27 0.65
2023-06-30 4.12 $2.14 1.93
2023-03-31 8.68 $1.80 4.81
2022-12-31 13.12 $4.80 2.73
2022-09-30 17.20 $7.60 2.26
2022-06-30 10.98 $11.67 0.94
2022-03-31 22.20 $17.05 1.30
2021-12-31 34.40 $22.23 1.55
2021-09-30 61.40 $26.04 2.36
2021-06-30 78.00 $30.14 2.59
2021-03-31 55.80 $28.38 1.97
2020-12-31 61.20 $34.95 1.75
2020-09-30 121.60 $44.38 2.74
2020-06-30 118.20 $47.46 2.49
2020-03-31 53.00 $58.76 0.90
2019-12-31 54.40 $70.82 0.77
2019-09-30 242.40 $86.79 2.79
2019-06-30 229.00 $103.02 2.22
2019-03-31 420.60 $-5.66 -74.34
Sector Industry Market Cap Revenue
Medical Medical - Biomedical and Genetics $0.005B $0.002B
Cyclerion Therapeutics Inc. is a clinical-stage biopharmaceutical company harnessing the power of sGC pharmacology to discover, develop and commercialize breakthrough treatments for serious and orphan diseases. The company's product pipeline consists of Olinciguat, Praliciguat and IW-6463 which are in clinical stage. Cyclerion Therapeutics Inc. is based in Cambridge, United States.
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Opthea (OPT) Australia $0.583B 0.00
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Eton Pharmaceuticals (ETON) United States $0.468B 0.00
DBV Technologies S.A (DBVT) France $0.466B 0.00
Bicycle Therapeutics (BCYC) United Kingdom $0.455B 0.00
Fulcrum Therapeutics (FULC) United States $0.452B 0.00
EnGene Holdings (ENGN) Canada $0.444B 0.00
Neurogene (NGNE) United States $0.444B 0.00
Design Therapeutics (DSGN) United States $0.433B 0.00
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Kamada (KMDA) Israel $0.419B 20.22
Ocugen (OCGN) United States $0.419B 0.00
Invivyd (IVVD) United States $0.413B 0.00
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Zura Bio (ZURA) United States $0.301B 0.00
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Eupraxia Pharmaceuticals (EPRX) Canada $0.237B 0.00
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ProQR Therapeutics (PRQR) Netherlands $0.227B 0.00
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Nautilus Biotechnology (NAUT) United States $0.219B 0.00
GENFIT S.A (GNFT) France $0.217B 0.00
Adocia (ADOCY) France $0.216B 0.00
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Tiziana Life Sciences (TLSA) United Kingdom $0.208B 0.00
Humacyte (HUMA) United States $0.198B 0.00
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Forte Biosciences (FBRX) United States $0.180B 0.00
Innate Pharma S.A (IPHA) France $0.177B 0.00
C4 Therapeutics (CCCC) United States $0.177B 0.00
Codexis (CDXS) United States $0.174B 0.00
MaxCyte (MXCT) United States $0.168B 0.00
PepGen (PEPG) United States $0.168B 0.00
Molecular Partners AG (MOLN) Switzerland $0.167B 0.00
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Milestone Pharmaceuticals (MIST) Canada $0.164B 0.00
Sangamo Therapeutics (SGMO) United States $0.158B 0.00
Nuvectis Pharma (NVCT) United States $0.154B 0.00
Rani Therapeutics Holdings (RANI) United States $0.152B 0.00
Cognition Therapeutics (CGTX) United States $0.152B 0.00
Cardiff Oncology (CRDF) United States $0.151B 0.00
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Compugen (CGEN) Israel $0.150B 0.00
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Actuate Therapeutics (ACTU) United States $0.146B 0.00
Alector (ALEC) United States $0.146B 0.00
Anika Therapeutics (ANIK) United States $0.146B 0.00
Seres Therapeutics (MCRB) United States $0.145B 0.00
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Scilex Holding (SCLX) United States $0.144B 0.00
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Entera Bio (ENTX) Israel $0.133B 0.00
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Climb Bio (CLYM) United States $0.131B 0.00
BioHarvest Sciences (BHST) Canada $0.130B 0.00
Alpha Cognition (ACOG) Canada $0.128B 0.00
Immix Biopharma (IMMX) United States $0.125B 0.00
VistaGen Therapeutics (VTGN) United States $0.125B 0.00
Opus Genetics (IRD) United States $0.125B 0.00
Turn Therapeutics (TTRX) United States $0.123B 0.00
VTv Therapeutics (VTVT) United States $0.122B 0.00
Fate Therapeutics (FATE) United States $0.120B 0.00
Starpharma Holdings (SPHRY) Australia $0.119B 0.00
Acumen Pharmaceuticals (ABOS) United States $0.118B 0.00
Seer (SEER) United States $0.117B 0.00
Greenwich LifeSciences (GLSI) United States $0.115B 0.00
TuHURA Biosciences (HURA) United States $0.114B 0.00
Oncolytics Biotech (ONCY) Canada $0.114B 0.00
Eledon Pharmaceuticals (ELDN) United States $0.113B 0.00
Citius Oncology (CTOR) United States $0.112B 0.00
Pliant Therapeutics (PLRX) United States $0.111B 0.00
Whitehawk Therapeutics (WHWK) United States $0.105B 0.00
Inovio Pharmaceuticals (INO) United States $0.105B 0.00
Coya Therapeutics (COYA) United States $0.102B 0.00
Zhengye Biotechnology Holding (ZYBT) China $0.102B 0.00
Instil Bio (TIL) United States $0.101B 0.00
InflaRx (IFRX) Germany $0.098B 0.00
OKYO Pharma (OKYO) $0.098B 0.00
Anebulo Pharmaceuticals (ANEB) United States $0.097B 0.00
Artiva Biotherapeutics (ARTV) United States $0.097B 0.00
Biomea Fusion (BMEA) United States $0.097B 0.00
Zentalis Pharmaceuticals (ZNTL) United States $0.097B 0.00
Adverum Biotechnologies (ADVM) United States $0.095B 0.00
Clene (CLNN) United States $0.095B 0.00
Ovid Therapeutics (OVID) United States $0.094B 0.00
Chrome Holding (MEHCQ) United States $0.093B 0.00
Kalaris Therapeutics (KLRS) United States $0.093B 0.00
Shattuck Labs (STTK) United States $0.092B 0.00
Quince Therapeutics (QNCX) United States $0.092B 0.00
Tevogen Bio Holdings (TVGN) United States $0.092B 0.00
Connect Biopharma Holdings (CNTB) United States $0.090B 0.00
CAMP4 Therapeutics (CAMP) United States $0.089B 0.00
Atara Biotherapeutics (ATRA) United States $0.088B 5.72
BeyondSpring (BYSI) United States $0.086B 0.00
Leap Therapeutics (LPTX) United States $0.085B 0.00
XBiotech (XBIT) United States $0.084B 0.00
Adagene (ADAG) China $0.083B 0.00
Precision BioSciences (DTIL) United States $0.080B 0.00
BioStem Technologies (BSEM) $0.078B 4.08
Fortress Biotech (FBIO) United States $0.078B 0.00
Estrella Immunopharma (ESLA) United States $0.078B 0.00
Immunic (IMUX) United States $0.075B 0.00
Repare Therapeutics (RPTX) Canada $0.074B 0.00
ABVC BioPharma (ABVC) United States $0.073B 0.00
ATyr Pharma (ATYR) United States $0.071B 0.00
Coeptis Therapeutics Holdings (COEP) United States $0.070B 0.00
ALX Oncology Holdings (ALXO) United States $0.069B 0.00
Sutro Biopharma (STRO) United States $0.069B 0.00
Vor Biopharma (VOR) $0.069B 0.00
CervoMed (CRVO) United States $0.069B 0.00
TScan Therapeutics (TCRX) United States $0.068B 0.00
MiNK Therapeutics (INKT) United States $0.062B 0.00
Adlai Nortye (ANL) Cayman Islands $0.059B 0.00
Annovis Bio (ANVS) United States $0.059B 0.00
Adicet Bio (ACET) United States $0.057B 0.00
Oncobiologics (OTLK) United States $0.057B 0.00
Equillium (EQ) United States $0.055B 0.00
Werewolf Therapeutics (HOWL) United States $0.053B 0.00
Spruce Biosciences (SPRB) United States $0.051B 0.00
Cue Biopharma (CUE) United States $0.051B 0.00
Senti Biosciences (SNTI) United States $0.049B 0.00
Skye Bioscience (SKYE) United States $0.049B 0.00
CalciMedica (CALC) United States $0.048B 0.00
PDS Biotechnology (PDSB) United States $0.045B 0.00
TELA Bio (TELA) United States $0.045B 0.00
Kezar Life Sciences (KZR) United States $0.045B 0.00
Celularity (CELU) United States $0.045B 0.00
Mersana Therapeutics (MRSN) United States $0.044B 0.00
X4 Pharmaceuticals (XFOR) United States $0.044B 0.00
Radiopharm Theranostics - (RADX) Australia $0.043B 0.00
Medicus Pharma (MDCX) United States $0.043B 0.00
Genenta Science S.p.A (GNTA) Italy $0.043B 0.00
LAVA Therapeutics (LVTX) Netherlands $0.042B 0.00
Grace Therapeutics (GRCE) Canada $0.042B 0.00
OnKure Therapeutics (OKUR) United States $0.042B 0.00
INmune Bio (INMB) United States $0.040B 0.00
BioAtla (BCAB) United States $0.040B 0.00
Xilio Therapeutics (XLO) United States $0.040B 0.00
Tvardi Therapeutics (TVRD) United States $0.040B 0.00
Aligos Therapeutics (ALGS) United States $0.040B 0.00
Lantern Pharma (LTRN) United States $0.038B 0.00
Hyperion DeFi (HYPD) United States $0.038B 0.00
Generation Bio (GBIO) United States $0.037B 0.00
RenovoRx (RNXT) United States $0.037B 0.00
Pluri (PLUR) Israel $0.036B 0.00
SAB Biotherapeutics (SABS) United States $0.036B 0.00
ImageneBio (IMA) United States $0.034B 0.00
Dyadic (DYAI) United States $0.034B 0.00
Rein Therapeutics (RNTX) United States $0.034B 0.00
Sonnet BioTherapeutics Holdings (SONN) United States $0.034B 0.00
Alterity Therapeutics - (ATHE) Australia $0.034B 0.00
Barinthus Biotherapeutics (BRNS) United States $0.033B 0.00
AN2 Therapeutics (ANTX) United States $0.032B 0.00
Tenax Therapeutics (TENX) United States $0.032B 0.00
Quantum Biopharma (QNTM) Canada $0.032B 0.00
Elutia (ELUT) United States $0.031B 0.00
Femasys (FEMY) United States $0.031B 0.00
Galecto (GLTO) Denmark $0.031B 0.00
Intensity Therapeutics (INTS) United States $0.031B 0.00
Passage Bio (PASG) United States $0.030B 0.00
Q32 Bio (QTTB) United States $0.030B 0.00
Rallybio (RLYB) United States $0.030B 0.00
Jasper Therapeutics (JSPR) United States $0.029B 0.00
Boundless Bio (BOLD) United States $0.028B 0.00
BioXcel Therapeutics (BTAI) United States $0.027B 0.00
MIRA Pharmaceuticals (MIRA) United States $0.027B 0.00
Lixte Biotechnology Holdings (LIXT) United States $0.027B 0.00
Dare Bioscience (DARE) United States $0.027B 0.00
Synaptogenix (TAOX) United States $0.026B 0.00
Cadrenal Therapeutics (CVKD) United States $0.025B 0.00
Lexaria Bioscience (LEXX) Canada $0.025B 0.00
IBio (IBIO) United States $0.025B 0.00
NextCure (NXTC) United States $0.025B 0.00
Tharimmune (THAR) United States $0.025B 0.00
Moleculin Biotech (MBRX) United States $0.024B 0.00
CollPlant Biotechnologies (CLGN) Israel $0.024B 0.00
Exicure (XCUR) United States $0.023B 0.00
Promis Neurosciences (PMN) Canada $0.022B 0.00
Aytu BioPharma (AYTU) United States $0.021B 0.00
Cingulate (CING) United States $0.021B 0.00
Clearside Biomedical (CLSD) United States $0.020B 0.00
Synlogic (SYBX) United States $0.020B 0.00
Lisata Therapeutics (LSTA) United States $0.019B 0.00
Athira Pharma (ATHA) United States $0.019B 0.00
Allarity Therapeutics (ALLR) United States $0.018B 0.00
Apollomics (APLM) United States $0.018B 0.00
Akari Therapeutics (AKTX) United Kingdom $0.018B 0.00
MetaVia (MTVA) United States $0.017B 0.00
Hoth Therapeutics (HOTH) United States $0.017B 0.00
FibroBiologics (FBLG) United States $0.017B 0.00
NewcelX (NCEL) Switzerland $0.017B 0.00
Abpro Holdings (ABP) United States $0.016B 0.00
Curis (CRIS) United States $0.016B 0.00
Cuprina Holdings (Cayman) (CUPR) Singapore $0.016B 0.00
Revelation Biosciences (REVB) United States $0.015B 0.00
Longeveron (LGVN) United States $0.015B 0.00
GeoVax Labs (GOVX) United States $0.015B 0.00
Chemomab Therapeutics (CMMB) Israel $0.014B 0.00
BioCardia (BCDA) United States $0.014B 0.00
Dogwood Therapeutics (DWTX) United States $0.013B 0.00
Sensei Biotherapeutics (SNSE) United States $0.013B 0.00
Edesa Biotech (EDSA) Canada $0.013B 0.00
Novogen (KZIA) Australia $0.013B 0.00
Beyond Air (XAIR) United States $0.012B 0.00
Neuphoria Therapeutics (NEUP) Australia $0.012B 0.00
Biofrontera (BFRI) United States $0.011B 0.00
Cocrystal Pharma (COCP) United States $0.011B 0.00
Biorestorative Therapies (BRTX) United States $0.011B 0.00
IMMURON (IMRN) Australia $0.011B 0.00
Propanc Biopharma Inc (PPCB) Australia $0.011B 0.00
Acurx Pharmaceuticals (ACXP) United States $0.010B 0.00
Purple Biotech (PPBT) Israel $0.010B 0.00
Gelteq (GELS) Australia $0.010B 0.00
Advanced Biomed (ADVB) United States $0.010B 0.00
Imunon (IMNN) United States $0.010B 0.00
Silexion Therapeutics Corp (SLXN) Israel $0.009B 0.00
Mustang Bio (MBIO) United States $0.009B 0.00
Bolt Biotherapeutics (BOLT) United States $0.009B 0.00
Sunshine Biopharma (SBFM) United States $0.009B 0.00
BioAffinity Technologies (BIAF) United States $0.008B 0.00
Creative Medical Technology Holdings (CELZ) United States $0.008B 0.00
Avalon GloboCare (ALBT) United States $0.008B 0.00
Mainz Biomed (MYNZ) Germany $0.007B 0.00
Alzamend Neuro (ALZN) United States $0.007B 0.00
Aprea Therapeutics (APRE) United States $0.007B 0.00
Adial Pharmaceuticals (ADIL) United States $0.007B 0.00
IN8bio (INAB) United States $0.007B 0.00
BRIACELL THERAP (BCTX) Canada $0.007B 0.00
Evogene (EVGN) Israel $0.007B 0.00
Bionano Genomics (BNGO) United States $0.007B 0.00
Cardio Diagnostics Holdings (CDIO) United States $0.007B 0.00
Entero Therapeutics (ENTO) United States $0.006B 0.00
Ensysce Biosciences (ENSC) United States $0.006B 0.00
Silo Pharma (SILO) United States $0.006B 0.00
VivoSim Labs (VIVS) United States $0.006B 0.00
Soligenix (SNGX) United States $0.006B 0.00
GENPREX (GNPX) United States $0.006B 0.00
HCW Biologics (HCWB) United States $0.006B 0.00
Aspire Biopharma Holdings (ASBP) United States $0.005B 0.00
Pasithea Therapeutics (KTTA) United States $0.005B 0.00
KALA BIO (KALA) United States $0.005B 0.00
Polyrizon (PLRZ) Israel $0.005B 0.00
Arcadia Biosciences (RKDA) United States $0.005B 0.00
Aptevo Therapeutics (APVO) United States $0.005B 0.00
Psyence Biomedical (PBM) Canada $0.005B 0.00
GRI Bio (GRI) United States $0.005B 0.00
Black Titan (BTTC) United States $0.005B 0.00
AquaBounty Technologies (AQB) United States $0.004B 0.00
Onconetix (ONCO) United States $0.004B 0.00
CNS Pharmaceuticals (CNSP) United States $0.004B 0.00
Atrinsic (PTIX) United States $0.004B 0.00
Scinai Immunotherapeutics (SCNI) Israel $0.003B 0.00
Biodexa Pharmaceuticals (BDRX) United Kingdom $0.003B 0.00
Bone Biologics (BBLG) United States $0.003B 0.00
Enveric Biosciences (ENVB) United States $0.003B 0.00
Alps Group (ALPS) United States $0.003B 2.48
GT Biopharma (GTBP) United States $0.003B 0.00
Dermata Therapeutics (DRMA) United States $0.002B 0.00
Virax Biolabs Group (VRAX) United Kingdom $0.002B 0.00
Artelo Biosciences (ARTL) United States $0.001B 0.00
NuCana (NCNA) United Kingdom $0.000B 0.00
Aceragen (ACGN) United States $0.000B 0.00
ARAVIVE, INC (ARAV) United States $0.000B 0.00
Cellectis S.A (CLLS) France $0.000B 0.00
Clovis Oncology (CLVSQ) United States $0.000B 0.00
Celyad SA (CYAD) Belgium $0.000B 0.00
CytoMed Therapeutics (GDTC) Singapore $0.000B 0.00
Galapagos (GLPG) Belgium $0.000B 0.00
IO Biotech (IOBT) Denmark $0.000B 0.00
MediciNova (MNOV) United States $0.000B 0.00
Motif Bio Plc (MTFB) United Kingdom $0.000B 0.00
NeuroSense Therapeutics (NRSN) Israel $0.000B 0.00
PDL BioPharma (PDLI) United States $0.000B 0.00
Pulmatrix (PULM) United States $0.000B 0.00
TFF Pharmaceuticals (TFFP) United States $0.000B 0.00
VectivBio Holding AG (VECT) Switzerland $0.000B 0.00
YD Bio (YDES) $0.000B 0.00