The current metro area population of Port St. Lucie in 2026 is 581,000, a 1.22% increase from 2025.

• The metro area population of Port St. Lucie in 2025 was 574,000, a 1.59% increase from 2024.
• The metro area population of Port St. Lucie in 2024 was 565,000, a 1.62% increase from 2023.
• The metro area population of Port St. Lucie in 2023 was 556,000, a 2.02% increase from 2022.